NMS-859 - Moligand™,≥95% , CAS No.1449236-96-7

CAS: 1449236-96-7 Cat. No.: N651782 Fórmula: C₁₅H₁₂ClN₃O₃S Peso molecular: 349.79

GRADE & PURITY Moligand™, ≥95%

Synonyms

3-[(1,1-dioxido-1,2-benzisothiazol-3-yl)amino]phenyl chloroacetate | ZINC169324353 | 2-Chloro-N-(3-((1,1-dioxidobenzo[d]isothiazol-3-yl)amino)phenyl)acetamide

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

NMS-859 suppresses the cell proliferation with IC50s of 3.0 μM and 3.5 μM in HeLa and HCT116 cell lines, respectively. NMS-859 shows weak inhibitory activity against VCPC522T.

Specifications

Sinónimos

3-[(1,1-dioxido-1,2-benzisothiazol-3-yl)amino]phenyl chloroacetate | ZINC169324353 | 2-Chloro-N-(3-((1,1-dioxidobenzo[d]isothiazol-3-yl)amino)phenyl)acetamide

Especificaciones y pureza

Moligand™,≥95%

Mecanismos bioquímicos y fisiológicos

NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC 50 s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.

Condiciones de almacenamiento de almacenamiento

Store at -20°C,Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

INHIBITOR

Pureza

≥95%

Nombres e identificadores

• Peso molecular: 349.79

Propiedades químicas y físicas

• Solubilidad: DMSO : 50 mg/mL (142.94 mM; Need ultrasonic)

Preguntas frecuentes

What is the purity of this product?

This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1449236-96-7, the molecular formula is C15H12ClN3O3S, and the molecular weight is 349.79 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.