NODAGA-NHS , CAS No.1407166-70-4

CAS: 1407166-70-4 Cat. No.: N1424040 Fórmula: C₁₉H₂₈N₄O₁₀ Peso molecular: 472.45

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

NODAGA-NHS (NODA-GA-NHS ester) is a [64]Cu chelator and the dissociated form of DOTA-trastuzumab in vivo. NODAGA-NHS was added in 0.1 M borate buffer at a ratio of 5/20/100 and was able to effectively bind trastuzumab (10 mg/mL) (4°C, 20 h). The copper content of the [64]Cu-NODAGA-trastuzumab was up to 80%. After blood was drawn from the caudal vein of mice, [64]Cu-NODAGA-trastuzumab was injected and showed good tumor uptake in mice expressing HER2 tumors, showing good PET imaging tracking ability.

Specifications

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

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Nombres e identificadores

Peso molecular

472.45