NSC130813 - ≥95%(HPLC) , CAS No.1082532-95-3

CAS: 1082532-95-3 Cat. No.: N165828 Fórmula: C₂₆H₃₀Cl₄N₄O₂ Peso molecular: 572.35 PubChem CID: 146681187

GRADE & PURITY ≥95%(HPLC)

Synonyms

4-[(6-Chloro-2-methoxy-9-acridinyl)amino]-2-[(4-methyl-1-piperazinyl)methyl]-phenol trihydrochloride, F06, NERI02

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

4-[(6-Chloro-2-methoxy-9-acridinyl)amino]-2-[(4-methyl-1-piperazinyl)methyl]-phenol trihydrochloride, F06, NERI02

Especificaciones y pureza

≥95%(HPLC)

Mecanismos bioquímicos y fisiológicos

NSC130813 blocks protein-protein interactions between XPF and ERCC1, two proteins involved in nucleotide excision repair (NER). The compound, NSC130813, blocks repair of DNA damage induced by platinum-based ctyotoxic drugs and DNA alkylating agents. NSC13

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥95%(HPLC)

Nombres e identificadores

• Pubchem Sid: 504773637
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504773637
• Sonrisas canónicas: CN1CCN(CC1)CC2=C(C=CC(=C2)NC3=C4C=C(C=CC4=NC5=C3C=CC(=C5)Cl)OC)O.Cl.Cl.Cl
• IUPAC Name: 4-[(6-chloro-2-methoxyacridin-9-yl)amino]-2-[(4-methylpiperazin-1-yl)methyl]phenol;trihydrochloride
• InChIKey: LFCZLRJCUOEWSZ-UHFFFAOYSA-N
• INCHI: 1S/C26H27ClN4O2.3ClH/c1-30-9-11-31(12-10-30)16-17-13-19(4-8-25(17)32)28-26-21-6-3-18(27)14-24(21)29-23-7-5-20(33-2)15-22(23)26;;;/h3-8,13-15,32H,9-12,16H2,1-2H3,(H,28,29);3*1H
• WGK Alemania: 3
• PubChem CID: 146681187
• Peso molecular: 572.35

Propiedades químicas y físicas

• Solubilidad: H2O: 10 mg/mL, clear
• Sensibilidad: air sensitive

Preguntas frecuentes

What is the purity of this product, and how is it determined?

This product is supplied at ≥95% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1082532-95-3, the molecular formula is C26H30Cl4N4O2, and the molecular weight is 572.35 g/mol. InChIKey LFCZLRJCUOEWSZ-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.