OARV-771 - ≥98% , CAS No.2683008-37-7

CAS: 2683008-37-7 Cat. No.: O651646 Fórmula: C₄₉H₅₉ClN₈O₈S₂ Peso molecular: 987.62

CALIDAD & PUREZA ≥98%

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Application

PROTAC

Descripción general

OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC 50 s of 6, 1, and 4 nM for Brd4 , Brd2 and Brd3 , respectively

In Vitro

OARV-771 shows antiproliferative effect with an EC 50 value of 4 nM in MV4;11. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:BRD4 6 nM (DC 50 ) BRD2 1 nM (DC 50 ) BRD3 4 nM (DC 50 ) VHL

Especificaciones

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC 50 s of 6, 1, and 4 nM for Brd4 , Brd2 and Brd3 , respectively.

Condiciones de almacenamiento de almacenamiento

Store at -20°C,Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥98%

Nombres e identificadores

Peso molecular

987.62

Propiedades químicas y físicas

• Solubilidad: DMSO : 100 mg/mL (101.25 mM; Need ultrasonic)