Oxaprozin Potassium - ≥95% , Cyclooxygenase inhibitor, CAS No.174064-08-5, Cyclooxygenase inhibitor

CAS: 174064-08-5 Cat. No.: O671164 Molecular Weight: 331.4 PubChem CID: 23694685

GRADE & PURITY ≥95%

Synonyms

CHEMBL1200463 | 4,5-Diphenyl-2-oxazolepropanoic Acid, Potassium Salt | OXAPROZIN POTASSIUM [WHO-DD] | HY-B0808A | SCHEMBL8190699 | DTXCID0092245 | Q27284098 | OXAPROZIN POTASSIUM [ORANGE BOOK] | 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoate | potassium

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Oxaprozin potassium is an orally active and potent inhibitor of COX, with IC 50 values of 2.2 μM and 36 μM for human platelet COX-1 and for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin potassium induces cell apoptosis. Oxaprozin potassium also inhibits the NF-κB activation. Oxaprozin potassium-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties

Specifications

Synonyms

CHEMBL1200463 | 4, 5-Diphenyl-2-oxazolepropanoic Acid, Potassium Salt | OXAPROZIN POTASSIUM [WHO-DD] | HY-B0808A | SCHEMBL8190699 | DTXCID0092245 | Q27284098 | OXAPROZIN POTASSIUM [ORANGE BOOK] | 3-(4, 5-diphenyl-1, 3-oxazol-2-yl)propanoate | potassium

Specifications & Purity

≥95%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Mechanism of action

Cyclooxygenase inhibitor

Purity

≥95%

Names and Identifiers

• Canonical Smiles: C1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)[O-])C3=CC=CC=C3.[K+]
• IUPAC Name: potassium;3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoate
• InChIKey: QTAQWNSMRSLSCG-UHFFFAOYSA-M
• INCHI: 1S/C18H15NO3.K/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14;/h1-10H,11-12H2,(H,20,21);/q;+1/p-1
• Isomeric SMILES: C1=CC=C(C=C1)C2=C(OC(=N2)CCC(=O)[O-])C3=CC=CC=C3.[K+]
• PubChem CID: 23694685
• Molecular Weight: 331.4