P110 TFA - 10mM in DMSO , CAS No.P110(DMSO)

CAS: P110(DMSO) Cat. No.: P580476 Fórmula: C₁₀₀H₁₇₉N₄₅O₂₅(free) Peso molecular: 2411.78(free)

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

P110 P110 is a dynamin-related protein 1 (Drp1) -specific inhibitor that binds directly to Drp1.

Targets

Drp1

In vitro

P110 is a Drp1-specific inhibitor that binds directly to Drp1. In some cases, this binding inhibits translocation to the mitochondria or prevents mitochondrial docking.

In vivo

P110 treatment inhibits the interaction of fission proteins Fis1/Drp1, decreases mitochondrial fission, and improves bioenergetics in three different rat models of IR, including primary cardiomyocytes, ex vivo heart model, and an in vivo myocardial infarction model.

Cell Research(from reference)

Cell lines：Primary cardiac myocytes 

Concentrations：1 μmol/L 

Incubation Time：2h + 2 to 60 min 

Specifications

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

P110 is a dynamin-related protein 1 (Drp1)-specific inhibitor that binds directly to Drp1.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

• Peso molecular: 2411.78(free)

Propiedades químicas y físicas

• Solubilidad: Solubility (25°C) In vitro DMSO: 100 mg/mL (41.46 mM); Water: 100 mg/mL (41.46 mM); Ethanol: Insoluble