Paraformaldehyde-d2 - ≥99 atom% D,≥98%, used for - Deuterium labeling for metabolic and pharmacokinetic studies - synthesis of deuterated reference standards - Isotope effect investigations in reaction mechanisms - Mass spectrometry calibration various ap

CAS: 32008-59-6 Cat. No.: P345108 Molecular Weight: 32.04 (monomer) EC Number: 686-130-4

GRADE & PURITY ≥99 atom% D,≥98%

Synonyms

Paraformaldehyde-d2 | FORMALIN-D2 (20% W/W IN H2O) 99 ATOM % D | J-010288 | J-018598 | AT37380 | CD2O | DTXSID00168098 | Formaldehyde-d2 (~20per cent in D2O) | (2H)Formaldehyde | Formaldehyde-d2 (6CI,8CI,9CI) | dideuteriomethanone | Formaldehyde-d2 | Form

Storage

Protected from light,Room temperature,Argon charged,Desiccated

Shipped In

Normal

Overview

General description 

Paraformaldehyde-d2 98 atom % D, 98% (CP) is a high-purity isotope product with a unique chemical profile that belongs to the class of isotopes. Produced by Sigma-Aldrich, we are committed to providing quality isotope products and a reliable supply chain. Available in industrial and pre-pack quantities. 

Features and Benefits

 Features 

- High reactivity for various applications - Supports innovative research in drugdiscovery - Produces minimal side products - Suitable for a variety of biological studies 

Benefits 

- Streamlines the drug discoveryprocess - Enhances the effectiveness of biological assays - Improves the accuracy of metabolic studies - Supports the advancement of personalized medicine

Specifications

Synonyms

Paraformaldehyde-d2 | FORMALIN-D2 (20% W/W IN H2O) 99 ATOM % D | J-010288 | J-018598 | AT37380 | CD2O | DTXSID00168098 | Formaldehyde-d2 (~20per cent in D2O) | (2H)Formaldehyde | Formaldehyde-d2 (6CI, 8CI, 9CI) | dideuteriomethanone | Formaldehyde-d2 | Form

Specifications & Purity

≥99 atom% D, ≥98%

Application

- Deuterium labeling for metabolic and pharmacokinetic studies - synthesis of deuterated reference standards - Isotope effect investigations in reaction mechanisms - Mass spectrometry calibration

Storage

Protected from light, Room temperature, Argon charged, Desiccated

Shipped In

Normal

Purity

≥99 atom% D, ≥98%

Names and Identifiers

• Canonical Smiles: C=O
• IUPAC Name: dideuteriomethanone
• InChIKey: WSFSSNUMVMOOMR-DICFDUPASA-N
• INCHI: 1S/CH2O/c1-2/h1H2/i1D2
• Isomeric SMILES: [2H]C(=O)[2H]
• WGK Germany: 2
• Alternate CAS: 30525-89-4（unlabelled）
• UN Number: 2213
• Packing Group: III
• Molecular Weight: 32.04 (monomer)

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Carbonyl compounds

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Carbonyl compounds
• Intermediate Tree Nodes: Not available
• Direct Parent: Carbonyl compounds
• Alternative Parents: Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Organic oxide - Hydrocarbon derivative - Carbonyl group - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as carbonyl compounds. These are organic compounds containing a carbonyl group, with the general structure RC(=O)R', where R=organyl, R'=H, N, O, organyl group or halide group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Aqueous Base (Sparingly), DMSO (Sparingly)
• Sensitivity: Moisture sensitive；light sensitive
• Melt Point(°C): 170° C (lit.)(dec.)
• Molecular Weight: 32.037 g/mol
• XLogP3: 1.200
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 32.0231 Da
• Monoisotopic Mass: 32.0231 Da
• Topological Polar Surface Area: 17.100 Ų
• Heavy Atom Count: 2
• Formal Charge: 0
• Complexity: 2.000
• Isotope Atom Count: 2
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Yarong Song, Yitong Zeng, Han Zheng, Shu Shi, Zhongqing Li, Mingchen Liu, Sijin Shao, Ziheng Luo, Yurong Li, Jie Li, Kuanhui Xiang, Jie Wang.  (2026)  SOX6 is a novel host factor that promotes hepatitis B virus replication by enhancing the transcriptional activity of enhancer I.  ANTIVIRAL RESEARCH,      [PMID:41616818] [10.1016/j.antiviral.2026.106359]