≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
PARP10-IN-2 is a potent mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC 50 of 3.64 μM for human PARP10 . PARP10-IN-2 reveals potent inhibition on PARP2 and PARP15 with IC 50 s of 27 μM and 11 μM for human PARP2 and human PARP15 , respectively
In Vitro
PARP10-IN-2 (compound 10) has an IC 50 of 1-2 μM by olony‐formation assay (CFA) in HeLa‐PARP10 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:human PARP10 3.64 μM (IC 50 ) human PARP15 11 μM (IC 50 ) human PARP2 27 μM (IC 50 ) human PARP12 >10 μM (IC 50 ) human PARP16 >10 μM (IC 50 ) human PARP1 >100 μM (IC 50 ) human PARP3 >100 μM (IC 50 ) human PARP4 >100 μM (IC 50 ) human TNKS1 >100 μM (IC 50 ) human TNKS2 >100 μM (IC 50 ) human PARP14 >100 μM (IC 50 )
Specifications
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
PARP10-IN-2 is a potent mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC 50 of 3.64 μM for human PARP10 . PARP10-IN-2 reveals potent inhibition on PARP2 and PARP15 with IC 50 s of 27 μM and 11 μM for human PARP2 and human PARP15 , respectively
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
INHIBITOR
Pureza
≥98%
Nombres e identificadores
Peso molecular
238.24
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Solubilidad
DMSO : 250 mg/mL (1049.36 mM; Need ultrasonic)
Calculadoras de soluciones
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Reseñas
Reseñas de cliente
Preguntas frecuentes
What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 1042780-52-8, the molecular formula is C14H10N2O2, and the molecular weight is 238.24 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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