PDE9-IN-1 - ≥99% , CAS No.2305087-92-5

CAS: 2305087-92-5 Cat. No.: P648498 Fórmula: C₁₇H₂₃FN₆O₂ Peso molecular: 362.40

CALIDAD & PUREZA ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

PDE9-IN-1 is a potent, selective, and orally bioavailable phosphodiesterase-9A (PDE9A) Inhibitor with an IC 50 of 8.7 nM

In Vitro

PDE9-IN-1 is excellent selectivity across PDE families. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

PDE9-IN-1 (2.5 and 5.0 mg/kg; Oral administration; daily for 21 days) effectively recovers learning and memory function . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Unilateral common carotid artery occlusion (UCCAO) mouse model Dosage: 2.5 and 5.0 mg/kg Administration: Oral administration; daily for 21 days Result: Significantly reduced the day 6 escape latency time and increased the frequency of platform area crossings, and recovered learning and memory function. High dose group possibly improved the escape latency time of mice.

Form:Solid

IC50& Target:PDE9A 8.7 nM (IC 50 )

Especificaciones

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

PDE9-IN-1 is a potent, selective, and orally bioavailable phosphodiesterase-9A (PDE9A) Inhibitor with an IC 50 of 8.7 nM.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥99%

Nombres e identificadores

Peso molecular

362.40

Propiedades químicas y físicas

• Solubilidad: DMSO : 100 mg/mL (275.94 mM; Need ultrasonic)

Preguntas frecuentes

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2305087-92-5, the molecular formula is C17H23FN6O2, and the molecular weight is 362.40 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.