PLX7922 - 10mM in DMSO , CAS No.1638772-61-8

CAS: 1638772-61-8 Cat. No.: P656692 Fórmula: \n C₂₀H₂₅FN₆O₂S₂ Peso molecular: 464.58 PubChem CID: 91971376

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

PLX7922, a RAF inhibitor, can bind with BRAF V600E . PLX7922 inhibits pERK in BRAF V600E cell lines, and activates pERK in mutant NRAS cell lines

In Vitro

PLX7922 (1-1000 nM) inhibits pERK in BRAF V600E cell lines, activates pERK in mutant NRAS cell lines (B9 and IPC-298). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:RAF

Specifications

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

PLX7922, a RAF inhibitor, can bind with BRAF V600E . PLX7922 inhibits pERK in BRAF V600E cell lines, and activates pERK in mutant NRAS cell lines.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Nombres e identificadores

• Isómeros SMILES: CCN(C)S(=O)(=O)NC1=CC=CC(=C1F)C2=C(SC(=N2)C(C)(C)C)C3=NC(=NC=C3)N
• PubChem CID: 91971376
• Peso molecular: 464.58