Potassium Oxonate - 10mM in Water , CAS No.2207-75-2

CAS: 2207-75-2 Cat. No.: P422648 Fórmula: C₄H₂KN₃O₄ Peso molecular: 195.18 Beilstein Registry Number: 24451 Número EC: 218-627-5 PubChem CID: 2723920

GRADE & PURITY 10mM in Water

Synonyms

Potassium oxonate|2207-75-2|Oteracil potassium|Oxonic acid potassium salt|Allantoxanic acid potassium salt|potassium 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylate|Potassium azaorotate|Oxonic acid, potassium salt|Oxonate|Potassium 2,6-dihydroxy

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Oxonic acid potassium salt is an inhibitor of uricase. The product has been used for the inhibition of 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats.It has also been used to induce hyperuricemia in rats; as it inhibits uric acid metabolism.

Specifications

Sinónimos

Potassium oxonate | 2207-75-2 | Oteracil potassium | Oxonic acid potassium salt | Allantoxanic acid potassium salt | potassium 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylate | Potassium azaorotate | Oxonic acid, potassium salt | Oxonate | Potassium 2,6-dihydroxy

Especificaciones y pureza

10mM in Water

Mecanismos bioquímicos y fisiológicos

Uricase inhibitor. Used to induce hyperuricemia in rats as it inhibits uric acid metabolism. Inhibits 5-fluorouracil-induced gastrointestinal toxicity without the loss of its antitumor activity in rats.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

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Nombres e identificadores

Pubchem Sid

528772529

Sonrisas canónicas

C1(=NC(=O)NC(=O)N1)C(=O)[O-].[K+]

IUPAC Name

potassium;4,6-dioxo-1H-1,3,5-triazine-2-carboxylate

InChIKey

IAPCTXZQXAVYNG-UHFFFAOYSA-M

INCHI

1S/C4H3N3O4.K/c8-2(9)1-5-3(10)7-4(11)6-1;/h(H,8,9)(H2,5,6,7,10,11);/q;+1/p-1

Isómeros SMILES

C1(=NC(=O)NC(=O)N1)C(=O)[O-].[K+]

WGK Alemania

3

RTECS

RR4580000

PubChem CID

2723920

Peso molecular

195.18

Beilstein

24451

Reaxy-Rn

4049961

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Triazines
      • Subclass Triazinones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Triazines
• Subclass: Triazinones
• Intermediate Tree Nodes: Not available
• Direct Parent: Triazinones
• Alternative Parents: 1,3,5-triazines Heteroaromatic compounds Ureas Carboxylic acid salts Monocarboxylic acids and derivatives Carboxylic acids Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic potassium salts Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Triazinone - 1,3,5-triazine - Heteroaromatic compound - Carboxylic acid salt - Urea - Carboxylic acid derivative - Carboxylic acid - Monocarboxylic acid or derivatives - Azacycle - Organic alkali metal salt - Organic nitrogen compound - Organic salt - Organic potassium salt - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aromatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as triazinones. These are compounds containing a triazine ring which bears a ketone group a carbon atom.
• External Descriptors: organic molecular entity

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (no humanos)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Punto de fusión (°C): 300 °C
• Peso molecular: 195.170 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 194.968 Da
• Monoisotopic Mass: 194.968 Da
• Topological Polar Surface Area: 111.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 273.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3