Rapamycin-D3 - ≥98% deuterated forms(d1-d3), 1mg/ml in ethanol , CAS No.392711-19-2

CAS: 392711-19-2 Cat. No.: R334644 Molecular Weight: 917.19

GRADE & PURITY ≥98% deuterated forms(d1-d3), 1mg/ml in ethanol

Synonyms

(?)-Rapamycin-d3 | AY 22989-d3 | Antibiotic AY 22989-d3 | Sirolimus-D3 | 7-O-demethyl-7-O-(methyl-d3)-rapamycin

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Product Describtion:

Rapamycin-d3is a labeled Rapamycin. It is also a triene macrolide antibiotic isolated from|Streptomyces hygroscopicus|Its name was derived from the native word for Easter Island, Rapa′Nui. It can be used as an immunosuppressant and antirestenotic.  Rapamycin-d3 is an inhibitor of mTOR. 

Specifications

Synonyms

(?)-Rapamycin-d3 | AY 22989-d3 | Antibiotic AY 22989-d3 | Sirolimus-D3 | 7-O-demethyl-7-O-(methyl-d3)-rapamycin

Specifications & Purity

≥98% deuterated forms(d1-d3), 1mg/ml in ethanol

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥98% deuterated forms(d1-d3)

Names and Identifiers

• Canonical Smiles: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O)C1(O2)O)C(C)CC4CCC(C(C4)OC)O)C)C)O)OC)C)C)C)OC
• IUPAC Name: (1R,9S,12S,15R,16Z,18R,19R,21R,23S,24Z,26Z,28Z,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19-methoxy-15,17,21,23,29,35-hexamethyl-30-(trideuteriomethoxy)-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
• InChIKey: QFJCIRLUMZQUOT-NWORAYHKSA-N
• INCHI: 1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11-,16-12-,31-17-,35-25-/t30-,32-,33-,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1/i8D3
• Alternate CAS: 53123-88-9（unlabelled）
• Molecular Weight: 917.19

Chemical and Physical Properties

• Solubility: Soluble in Dichloromethane and Methanol
• Sensitivity: Moisture sensitive.
• Melt Point(°C): 101-103° C