Remodelin hydrobromide - 10mM in DMSO , CAS No.1622921-15-6

CAS: 1622921-15-6 Cat. No.: R408429 Fórmula: C₁₅H₁₅BrN₄S Peso molecular: 363.28 PubChem CID: 86280479

GRADE & PURITY 10mM in DMSO

Synonyms

Remodelin HBr | 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile, hydrobromide (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Remodelin hydrobromide Remodelin hydrobromide (HBr) is a potent acetyl-transferase NAT10 inhibitor.
In vitro

Remodelin, via inhibition of NAT10, mediates nuclear shape rescue of LMNA depleted cells by microtubule reorganization, and improves nuclear shape and fitness of HGPS cells. Remodelin may thus provide opportunities for alleviating dystrophic and premature-ageing diseases.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

Remodelin HBr | 4-[2-(2-cyclopentylidenehydrazinyl)-4-thiazolyl]-benzonitrile, hydrobromide (1:1)

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Remodelin hydrobromide (HBr) is a potent acetyl-transferase NAT10 inhibitor.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Propiedades del producto

• ALogP: 4.031
• Recuento HBD: 1
• Enlace rotable: 3

Nombres e identificadores

• Isómeros SMILES: C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)C#N)C1.Br
• PubChem CID: 86280479
• Peso molecular: 363.28

Propiedades químicas y físicas

• DMSO (mg/ml) Solubilidad máxima: 72
• DMSO (mM) Solubilidad máxima: 198.1942303
• Agua (mg/ml) Solubilidad máxima: ＜1

Preguntas frecuentes

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1622921-15-6, the molecular formula is C15H15BrN4S, and the molecular weight is 363.28 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.