| 1. Taorong Shen, Xing Huang, Yanfei Zhang, Yanli Tong, Yakun Shi, Jianhe Guo, Xiaoyong Zou, Yuzhi Xu, Zong Dai. (2023) Dephosphorylation Switch DNAzyme-RCA Circuit: A Robust Strategy for the Homogeneous and Reliable Detection of FTO Demethylase. ANALYTICAL CHEMISTRY, [PMID:38118402] [10.1021/acs.analchem.3c04762] |
| 2. Bi Wang, Jingjing Yang, Xingzeng Zhao, Xu Feng, Shu Xu, Pirui Li, Linwei Li, Yu Chen. (2023) Antifungal activity of the botanical compound rhein against Phytophthora capsici and the underlying mechanisms. PEST MANAGEMENT SCIENCE, [PMID:37897133] [10.1002/ps.7852] |
| 3. Yan Zhou, Tian-Xiu Qiu, Huan Wang, Ling Hu, Lei Liu, Jiong Chen. (2023) Application of rhein as an immunostimulant controls spring viremia of carp virus infection. FISH & SHELLFISH IMMUNOLOGY, [PMID:37777100] [10.1016/j.fsi.2023.109128] |
| 4. Rongkun Zhu, Zengcheng Du, Mingfang Zhu, Huanru Liang, Shumei Wang, Qing Zhou, Rui Li, Yulan Li, Chaoying Zeng, Wenhao Liu, Qiqing Chen. (2023) Molecularly imprinted polymers embedded with double perovskite quantum dots: A ratiometric fluorescence sensor for visible and fluorescent determination of Rhein. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2023.143618] |
| 5. Wan Li, Kexin Fang, Hao Yuan, Dongru Li, Haochen Li, Yin Chen, Xinyao Luo, Lian Zhang, Xiaochuan Ye. (2023) Acid-induced Poria cocos alkali-soluble polysaccharide hydrogel: Gelation behaviour, characteristics, and potential application in drug delivery. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:37030457] [10.1016/j.ijbiomac.2023.124383] |
| 6. Lei Zhang, Ying-Xuan Liu, Ya-Ting Yao, Tian-Jiao Zhou, Hu-Lin Jiang, Cheng-jun Li. (2023) Injectable rhein-assisted crosslinked hydrogel for efficient local osteosarcoma chemotherapy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, [PMID:36702387] [10.1016/j.ijpharm.2023.122637] |
| 7. Qing-Yun Hu, Junfeng Hu, Han Li, Xiaolin Fang, Zhi-Jun Sun, Zhigang Xu, Lu Zhang. (2022) Anti-inflammatory and antioxidant effects of rhein loaded nanomicelles in periodontitis. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2022.130164] |
| 8. Yongjun Wu, Yong Xie, Hongwei Shi. (2022) Determination and Model Correlation of Rhein in 12 Pure Solvents from 283.15 K to 323.15 K. JOURNAL OF CHEMICAL AND ENGINEERING DATA, [PMID:] [10.1021/acs.jced.2c00232] |
| 9. Yuanyuan Song, Ziqi Wang, Yijing Long, Yang Mao, Feng Jiang, Yuanyuan Lu. (2022) 2-Alkyl-anthraquinones inhibit Candida albicans biofilm via inhibiting the formation of matrix and hyphae. RESEARCH IN MICROBIOLOGY, [PMID:35550403] [10.1016/j.resmic.2022.103955] |
| 10. Zhihui Yin, Demin Gao, Ke Du, Chen Han, Yuhan Liu, Ying Wang, Xiaoyan Gao. (2022) Rhein Ameliorates Cognitive Impairment in an APP/PS1 Transgenic Mouse Model of Alzheimer’s Disease by Relieving Oxidative Stress through Activating the SIRT1/PGC-1α Pathway. Oxidative Medicine and Cellular Longevity, [PMID:35360200] [10.1155/2022/2524832] |
| 11. Rui Wang, Baifei Hu, Cheng Ye, Zhigang Zhang, Mingzhu Yin, Qiushi Cao, Yuanming Ba, Hongtao Liu. (2022) Stewed Rhubarb Decoction Ameliorates Adenine-Induced Chronic Renal Failure in Mice by Regulating Gut Microbiota Dysbiosis. Frontiers in Pharmacology, [PMID:35392552] [10.3389/fphar.2022.842720] |
| 12. Ying Xu, Xuan Yu, Jiaqi Gui, Yiqun Wan, Jinping Chen, Ting Tan, Fan Liu, Lan Guo. (2022) Ultrasonic Solvent Extraction Followed by Dispersive Solid Phase Extraction (d-SPE) Cleanup for the Simultaneous Determination of Five Anthraquinones in Polygonum multiflorum by UHPLC-PDA. Foods, 11 (3): (386). [PMID:35159536] [10.3390/foods11030386] |
| 13. Yin Zhihui, Geng Xinyue, Zhang Zhengyi, Wang Ying, Gao Xiaoyan. (2021) Rhein Relieves Oxidative Stress in an Aβ1-42 Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis. Frontiers in Pharmacology, [PMID:34566664] [10.3389/fphar.2021.746711] |
| 14. Jing Liang, Ke Min, Piao Long, Xuqian Weng, Qun Huang, Bo Chen, Ming Ma. (2021) Selective adsorption of flavonoids on cerium-doped ferroferric oxide magnetic particles. JOURNAL OF CHROMATOGRAPHY A, [PMID:33975082] [10.1016/j.chroma.2021.462189] |
| 15. Yan Zhang, Qing-nan Li, Kaiyue Zhou, Qinfeng Xu, Chun-yang Zhang. (2020) Identification of Specific N6-Methyladenosine RNA Demethylase FTO Inhibitors by Single-Quantum-Dot-Based FRET Nanosensors. ANALYTICAL CHEMISTRY, [PMID:32972135] [10.1021/acs.analchem.0c02828] |
| 16. Sun Xu, Xu Li, Jiang Weina, Xuan Yan, Lu Wen, Li Zhong, Yang Shilong, Gu Zhenzhen. (2020) Adsorption mechanism of rhein-coated Fe3O4 as magnetic adsorbent based on low-field NMR. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 28 (1): (1052-1060). [PMID:32829435] [10.1007/s11356-020-10541-5] |
| 17. Yunchang Fan, Zeyu Niu, Chen Xu, Lei Yang, Tuojie Yang. (2019) Protic Ionic Liquids as Efficient Solvents in Microwave-Assisted Extraction of Rhein and Emodin from Rheum palmatum L.. MOLECULES, 24 (15): (2770). [PMID:31366111] [10.3390/molecules24152770] |
| 18. Qingqing Hao, Lilin Lu, Xianwen Kan. (2019) Probe and analogue: Double roles of thionine for aloe-emodin selective and sensitive ratiometric detection. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2019.04.129] |
| 19. Yang Lehe, Lin Shichong, Kang Yanting, Xiang Youqun, Xu Lingyuan, Li Jifa, Dai Xuanxuan, Liang Guang, Huang Xiaoying, Zhao Chengguang. (2019) Rhein sensitizes human pancreatic cancer cells to EGFR inhibitors by inhibiting STAT3 pathway. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 38 (1): (1-13). [PMID:30674340] [10.1186/s13046-018-1015-9] |
| 20. Pin Lv, Manshuo Liu, Rongqiang Liao, Yulin Zhao, Xiali Liao, Chuanzhu Gao, Bo Yang. (2017) Host–guest inclusion system of rhein with polyamine-modified β-cyclodextrins: characterization and cytotoxicity. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, [PMID:27499262] [10.1080/10837450.2016.1221429] |
| 21. Xiaoya Jiang, Xiaoyan Jiao, Doudou Zhang, Ligai Bai, Haiyan Liu, Hongyuan Yan. (2017) Fabrication of a polymer monolithic column via redox system and its application in efficient separation of Chinese herb Rheum palmatum L.. JOURNAL OF APPLIED POLYMER SCIENCE, 134 (21): [PMID:] [10.1002/app.44874] |
| 22. Dong Jian-Wei, Cai Le, Fang Yun-Shan, Duan Wei-He, Li Zhen-Jie, Ding Zhong-Tao. (2016) Simultaneous, Simple and Rapid Determination of Five Bioactive Free Anthraquinones in Radix et Rhizoma Rhei by Quantitative 1H NMR. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 27 (11): (2120-2126). [PMID:] [10.5935/0103-5053.20160103] |
| 23. Manshuo Liu, Pin Lv, Rongqiang Liao, Yulin Zhao, Bo Yang. (2016) Synthesis, characterization and biological activity of Rhein-cyclodextrin conjugate. JOURNAL OF MOLECULAR STRUCTURE, [PMID:] [10.1016/j.molstruc.2016.08.047] |
| 24. Xingqiang Wu, Shuxuan Liang, Xusheng Ge, Yunkai Lv, Hanwen Sun. (2015) Synthesis and evaluation of dummy molecularly imprinted microspheres for the specific solid-phase extraction of six anthraquinones from slimming tea. JOURNAL OF SEPARATION SCIENCE, 38 (8): (1263-1270). [PMID:25677958] [10.1002/jssc.201401341] |
| 25. Gong Hao, He Zihao, Peng Anlin, Zhang Xin, Cheng Biao, Sun Yue, Zheng Ling, Huang Kun. (2014) Effects of several quinones on insulin aggregation. Scientific Reports, 4 (1): (1-8). [PMID:25008537] [10.1038/srep05648] |
| 26. Dan Li, Shaopu Liu, Yizhong Shen, Jidong Yang, Youqiu He. (2014) Molecular spectroscopic studies on the interactions of rhein and emodin with thioglycolic acid-capped core/shell CdTe/CdS quantum dots and their analytical applications. LUMINESCENCE, 30 (1): (60-66). [PMID:24850622] [10.1002/bio.2690] |
| 27. Ruibing Feng, Yu Fan, Xinya Zhang, Lanmei Chen, Zhang-Feng Zhong, Yitao Wang, Hua Yu, Qing-Wen Zhang, Guodong Li. (2024) A Biomimetic Multifunctional Nanoframework for Symptom Relief and Restorative Treatment of Acute Liver Failure. ACS Nano, [PMID:38294834] [10.1021/acsnano.4c00173] |
| 28. Xiaokang Zhu, Li Xie, Jinming Tian, Yang Jiang, Erqun Song, Yang Song. (2024) A multi-mode Rhein-based nano-platform synergizing ferrotherapy/chemotherapy-induced immunotherapy for enhanced tumor therapy. Acta Biomaterialia, [PMID:38570106] [10.1016/j.actbio.2024.03.030] |
| 29. Jiamei Song, Jiaqi Zeng, Xi Chen, Jiayu Wang, Ying Zhang, Yuhao Gao, Ruiqi Wang, Nan Jiang, Yuhui Lin, Rui Li. (2025) Anti-neuroinflammatory agent rhein lysinate-based self-assembled injectable hydrogel loaded with ZL006 for promoting post-stroke functional recovery. BIOMATERIALS, [PMID:39884131] [10.1016/j.biomaterials.2025.123124] |
| 30. Mengmeng Chen, Mingyang Xue, Yong Zhou, Chen Xu, Nan Jiang, Yuding Fan, Yan Meng. (2024) Antiviral effects of rhein on largemouth bass ranavirus (LMBRaV). FISH & SHELLFISH IMMUNOLOGY, [PMID:39521355] [10.1016/j.fsi.2024.110019] |
| 31. Xiaoliu Liang, Linyu Ding, Jiaxin Ma, Jiwei Li, Lei Cao, Hui Liu, Minglei Teng, Zhenjie Li, Yisheng Peng, Hu Chen, Yali Zheng, Hongwei Cheng, Gang Liu. (2024) Enhanced Mechanical Strength and Sustained Drug Release in Carrier-Free Silver-Coordinated Anthraquinone Natural Antibacterial Anti-Inflammatory Hydrogel for Infectious Wound Healing. Advanced Healthcare Materials, [PMID:38725393] [10.1002/adhm.202400841] |
| 32. Ningchao Luo, Lisha Ma, Ninghui Ma, Jiale Wei, Hongyan Zhang, Wanyu Jin, Yujie Li, Jingbin Shi, Yang Xiong. (2024) Hesperidin PLGA nanoparticles potentiate the efficacy of aPD-1 in treating triple negative breast cancer by regulating CCL2 and ADPN expression in cancer-associated adipocytes. INTERNATIONAL IMMUNOPHARMACOLOGY, [PMID:39098226] [10.1016/j.intimp.2024.112759] |
| 33. Wenjiao Fu, Mengyu Guo, Xuemei Zhou, Zhenzhen Wang, Jiufeng Sun, Yaling An, Tong Guan, Mingdi Hu, Jiayang Li, Ziwei Chen, Jinmin Ye, Xingfa Gao, George Fu Gao, Lianpan Dai, Yaling Wang, Chunying Chen. (2024) Injectable Hydrogel Mucosal Vaccine Elicits Protective Immunity against Respiratory Viruses. ACS Nano, [PMID:38620102] [10.1021/acsnano.4c00155] |
| 34. Zheng Cheng, Song Lanlan, Yu Chang, Zhu Lingye, Zhang Jing, Wang Ning, Liu Mengchu, Li Shini, Wang Liangxing, Shen Zhifa, Huang Xiaoying. (2024) Palindrome-mediated DNA nanotubes with cell-specific aptamers to improve targeted antitumor effects and reduce toxicity on non-small cell lung cancer. Science China-Life Sciences, [PMID:39609362] [10.1007/s11427-023-2556-4] |
| 35. Ning Xia, Fengli Gao, Gang Liu, Yong Chang, Lin Liu. (2024) Pyrroloquinoline quinone exhibiting peroxidase-mimicking property for colorimetric assays. ANALYTICA CHIMICA ACTA, [PMID:39643317] [10.1016/j.aca.2024.343468] |
| 36. Yuyang Li, Weiwei Chen, Jinxin Ma, Guoying Huang, Guangquan Li, Qiumei He, Xiangyu Kong, Ling Tang, Jinqing Chen, Wenyou Ding, Zhongbin Zhang, Wenya Ding. (2024) Rhein against Staphylococcus xylosus by interfering with respiratory metabolism and inducing oxidative stress. Current Research in Food Science, [PMID:38545378] [10.1016/j.crfs.2024.100718] |
| 37. Xiaoliu Liang, Hui Liu, Hu Chen, Xuqi Peng, Zhenjie Li, Minglei Teng, Yisheng Peng, Jiwei Li, Linyu Ding, Jingsong Mao, Chengchao Chu, Hongwei Cheng, Gang Liu. (2024) Rhein-based Pickering emulsion for hepatocellular carcinoma: Shaping the metabolic signaling and immunoactivation in transarterial chemoembolization. Aggregate, [PMID:] [10.1002/agt2.552] |
| 38. Shuang Cai, Linlin Wang, Xilong Cui, Xinshu Zou, Sidi Zheng, Fanhui Liu, Chun Shi, Yanhua Li, Zhiyun Zhang. (2024) Rhein-loaded chitosan nanoparticles for treatment of MRSA-infected wound. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:39242008] [10.1016/j.ijbiomac.2024.135360] |
| 39. Xinke Yu, Sili Liu, Zhili Wan, Xiaoquan Yang. (2025) Bioactive herbal supramolecular hydrogels with a hierarchical nanofibrillar structure via metal ion mediated co-assembly. Nanoscale, [PMID:40765251] [10.1039/D5NR02063H] |
| 40. Yuhan Liu, Yu Lei, Luorui Shang, Zhaomin Yu, Li Wang, Jiabin Zhou, Guangtao Pan. (2025) Protective effects of Dachengqi Decoction in sepsis-associated liver injury based on network pharmacology analysis and experimental validation. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:40840728] [10.1016/j.jep.2025.120450] |
| 41. Dunsheng Liang, Xiao-Fan Shen, Ting-Ting Li, Yao Deng, Hong-Liang Xiao, Zhi-Peng Li, Shuan-Cheng Bai, Xiao-Yu Ma, Xiao-ping Liao, Dong-Hao Zhao, Hao Ren, Chaoqun Zhang, Jian Sun, Lu Han. (2025) A bionic yeast for the colon-targeted delivery of curcumin in the treatment of inflammatory bowel disease. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2025.164121] |
| 42. Yali Yuan, Jiayan Hu, Xinyu Lu, Haixiao Han, Muyuan Wang, Wenji Zhang, Yao Jiao, Yitong Li, Zhengdao Lin, Chengtao Liang, Yitong Yu, Chune Xie, Junxiang Li, Tangyou Mao. (2025) Oral rhein attenuate nonalcoholic steatohepatitis in mice through the modulation of gut microbiota and Th17 cell differentiation. PHYTOMEDICINE, [PMID:41110352] [10.1016/j.phymed.2025.157409] |
| 43. Peng Zhang, Cuicui Li, Huichang Gao, Kunpeng Hu. (2025) Biomimetic hybrid membrane-coated nanoparticles loaded with rhein-iron complex enhance ferroptosis and immunotherapy for triple-negative breast cancer. Materials Today Bio, [PMID:41551883] [10.1016/j.mtbio.2025.102747] |
| 44. Yanmei Li, Zixi Chen, Zigan Xu, Jinmei Wu, Dexin Yang, Yeye Yu, Ting Xie, Yong Dai, Shaodong Luan, Hanchao Gao. (2025) TMT-based quantitative proteomics and non-targeted metabolomics reveal the antibacterial mechanism of rhein against Bacillus cereus and its potential application as a food preservative. LWT-FOOD SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.lwt.2025.117487] |
| 45. Xinfu Lian, Yongjun Bai, Rong Xie, Wang Du, Lingbo Ma, Yuqian Jiang. (2026) Mechanistic insights into the anti-neuroinflammatory effects of cassia obtusifolia in Parkinson’s disease: a network pharmacology-based study. Frontiers in Aging Neuroscience, [PMID:41582997] [10.3389/fnagi.2025.1730009] |
| 46. Wei Sun, Lu Han, Yanyu Bi, Fangxu Yin, Rui Li, Yunbin Tong, Jingtian Zhang, Dan Ding, Daqing Sun. (2026) Mitochondrial fusion targeted supramolecular peptide hydrogel for gut neuroprotection. BIOMATERIALS, [PMID:41702228] [10.1016/j.biomaterials.2026.124061] |
| 47. Yong-An Yan, Siqi Han, Pian Jin, Xiao-Bo Zhao, Yan-Ping Shi, Wei Ha. (2026) An on-tissue chemical derivatization method for MALDI-MSI analysis of anthraquinones in mouse tissues. Analytical Methods, [PMID:41801015] [10.1039/D5AY01880C] |
| 48. Kebi Li, Xiaopei Wu, Peijun Xiong, Hanping He, Zinuo Xia, Yang Zhou, Liang Zhao, Jiaxin Li, Tao Liu, Hongwei Shi, Peihu Xu, Haixing Xu. (2026) Electroactive Dual-Drug Hydrogel-PLA Conduit for Nerve Regeneration. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 114 (4): (e70066). [PMID:] [10.1002/jbm.b.70066] |
| 49. Jiaxing Zhang, Wen Wang, Zubiyan Yibula, Xin Peng, Rongxin Su, Wei Qi. (2026) Anthraquinones Inhibit Insulin Amyloidosis in Crowded Environments. MOLECULES, 31 (7): (1092). [PMID:] [10.3390/molecules31071092] |
