RI(dl)-2 , CAS No.1902146-75-1

CAS: 1902146-75-1 Cat. No.: R1428053 Fórmula: C₁₉H₁₇N₃ Peso molecular: 287.4 PubChem CID: 127052567

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

RI(dl)-2 blocks RAD51 ’s D-loop activity in biochemical systems with an IC 50 value of 11.1 µM and inhibits homologous recombination ( HR ) activity with an IC 50 value of 3.0 µM. RI(dl)-2 inhibits HR -mediated repair of DNA double strand breaks and sensitizes different cancer cell lines.

Specifications

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

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Nombres e identificadores

• Sonrisas canónicas: CCNC1=CC=C(C=C1)C2=NC3=CC=CC=C3N4C2=CC=C4
• IUPAC Name: N-ethyl-4-pyrrolo[1,2-a]quinoxalin-4-ylaniline
• InChIKey: OEUMSXQHYXCNBG-UHFFFAOYSA-N
• INCHI: 1S/C19H17N3/c1-2-20-15-11-9-14(10-12-15)19-18-8-5-13-22(18)17-7-4-3-6-16(17)21-19/h3-13,20H,2H2,1H3
• Isómeros SMILES: CCNC1=CC=C(C=C1)C2=NC3=CC=CC=C3N4C2=CC=C4
• PubChem CID: 127052567
• Peso molecular: 287.4

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Diazanaphthalenes
      • Subclass Benzodiazines
        • Level5 Quinoxalines
          • Level6 Pyrroloquinoxalines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Diazanaphthalenes
• Subclass: Benzodiazines
• Intermediate Tree Nodes: Quinoxalines
• Direct Parent: Pyrroloquinoxalines
• Alternative Parents: Pyrrolopyrazines Phenylalkylamines Aniline and substituted anilines Secondary alkylarylamines Pyrazines Pyrroles Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Pyrroloquinoxaline - Pyrrolopyrazine - Phenylalkylamine - Aniline or substituted anilines - Secondary aliphatic/aromatic amine - Monocyclic benzene moiety - Pyrazine - Benzenoid - Pyrrole - Heteroaromatic compound - Azacycle - Secondary amine - Hydrocarbon derivative - Organopnictogen compound - Organonitrogen compound - Organic nitrogen compound - Amine - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as pyrroloquinoxalines. These are organic heterocyclic compounds containing a pyrrole ring fused to a quinoxaline ring system.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y