S 38093 - ≥98%(HPLC) , CAS No.1403835-45-9

CAS: 1403835-45-9 Cat. No.: S287735 Molecular Weight: 288.39 PubChem CID: 70941112

GRADE & PURITY ≥98%(HPLC)

Synonyms

rel-4-[3-[(3aR,6aS)-Hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]benzamide

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Synonyms

rel-4-[3-[(3aR, 6aS)-Hexahydrocyclopenta[c]pyrrol-2(1H)-yl]propoxy]benzamide

Specifications & Purity

≥98%(HPLC)

Biochemical and Physiological Mechanisms

H3antagonist and inverse agonist (Kivalues are 8.8, 1.2 and 1.44 μM, at rat, human and mouse, respectively). Exhibits no activity at other histaminergic receptors. Antagonizes agonist action at mouse H3receptors (KB= 0.65 μM). Displays inverse agonist act

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%(HPLC)

Names and Identifiers

• Canonical Smiles: C1CC2CN(CC2C1)CCCOC3=CC=C(C=C3)C(=O)N
• IUPAC Name: 4-[3-[(3aS,6aR)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]propoxy]benzamide
• InChIKey: MRNMYWNBLVJWKG-GASCZTMLSA-N
• INCHI: 1S/C17H24N2O2/c18-17(20)13-5-7-16(8-6-13)21-10-2-9-19-11-14-3-1-4-15(14)12-19/h5-8,14-15H,1-4,9-12H2,(H2,18,20)/t14-,15+
• Isomeric SMILES: C1C[C@@H]2CN(C[C@@H]2C1)CCCOC3=CC=C(C=C3)C(=O)N
• PubChem CID: 70941112
• Molecular Weight: 288.39

Associated Targets(Human)

HRH1 Tclin Histamine H1 receptor (7573 Activities)

Discover Target: HRH1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HRH3 Tclin Histamine H3 receptor (10389 Activities)

Discover Target: HRH3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Solvent:DMSO, Max Conc. mg/mL: 28.84, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 14.42, Max Conc. mM: 50