SAFit1 - 10mM in DMSO , CAS No.1643125-32-9

CAS: 1643125-32-9 Cat. No.: S655396 Fórmula: C₄₂H₅₃NO₁₁ Peso molecular: 747.87 PubChem CID: 86277875

CALIDAD & PUREZA 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

SAFit1 is a FK506 binding protein 51 ( FKBP51 )-specific inhibitor with a K i of 4±0.3 nM

In Vitro

SAFit1 (1-1000 nM) potently stimulates neurite outgrowth in two neuronal cell lines (N2a and SH-SY5Y) as well as in primary hippocampal neurons. SAFit1 is active over a wide concentration range. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Ki: 4±0.3 nM (FKBP51), >50000 nM (FKBP52)

Especificaciones

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

SAFit1 is a FK506 binding protein 51 ( FKBP51 )-specific inhibitor with a K i of 4±0.3 nM.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

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Nombres e identificadores

Isómeros SMILES

COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3C(=O)[C@@H](C4CCCCC4)C5=CC(=C(C(=C5)OC)OC)OC)OC

PubChem CID

86277875

Peso molecular

747.87

Objetivos asociados (humanos)

FKBP1A Tclin Peptidyl-prolyl cis-trans isomerase FKBP1A (0 Activities)

Discover Target: FKBP1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FKBP5 Tchem Peptidyl-prolyl cis-trans isomerase FKBP5 (0 Activities)

Discover Target: FKBP5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)