Semaglutide TFA - ≥99% , CAS No.S659061

CAS: S659061 Cat. No.: S659061 Fórmula: C₁₈₉H₂₉₂F₃N₄₅O₆₁ Peso molecular: 4227.66

CALIDAD & PUREZA ≥99%

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Semaglutide TFA, a long-acting GLP-1 analogue, is a Glukagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide TFA has the potential for type 2 diabetes treatment.

Appearance:Solid

IC50& Target:GLP-1 receptor .

In Vitro:Semaglutide has two amino acid substitutions compared to human GLP-1 (Aib 8 , Arg 34 ) and is derivatized at lysine 26. The GLP-1R affinity of Semaglutide is 0.38±0.06 nM. Semaglutide is a GLP-1 analogue with 94% sequence omology to human GLP-1.

In Vivo:The plasma half-life of Semaglutide is 46h in mini-pigs following i.v. administration and semaglutide has an MRT of 63.6h after s.c. dosing to mini-pigs . Semaglutide improves 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced motor impairme

Biological Activity:Semaglutide TFA, a long-acting GLP-1 analogue, is a Glukagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide TFA has the potential for type 2 diabetes treatment.

Especificaciones

Especificaciones y pureza

≥99%

Condiciones de almacenamiento de almacenamiento

Desiccated,Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥99%

Nombres e identificadores

Peso molecular

4227.66

Propiedades químicas y físicas

• Solubilidad: H2O : 100 mg/mL (23.65 mM; Need ultrasonic) DMSO : 100 mg/mL (23.65 mM; ultrasonic and warming and heat to 60°C)

Preguntas frecuentes

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?80 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is S659061, the molecular formula is C189H292F3N45O61, and the molecular weight is 4227.66 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.