SGC-SMARCA-BRDVIII - ≥99% , CAS No.1997319-84-2

CAS: 1997319-84-2 Cat. No.: S649566 Fórmula: C₁₉H₂₅N₅O₃ Peso molecular: 371.43

CALIDAD & PUREZA ≥99%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2/4 and PB1(5) , with K d s of 35 nM, 36 nM, and 13 nM, respectively. SGC-SMARCA-BRDVIII also inhibits PB1(2) and PB1(3) , with K d s of 3.7 and 2.0 μM, respectively. SGC-SMARCA-BRDVIII can block adipogenesis of 3T3-L1 murine fibroblasts

In Vitro

SGC-SMARCA-BRDVIII (compound 22) (1 μM; 14 days) blocks adipocyte differentiation in 3T3-L1 murine fibroblasts. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Kd: 35 nM (SMARCA2), 36 nM (SMARCA4), 13 nM (PB1(5))

Especificaciones

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2/4 and PB1(5) , with K d s of 35 nM, 36 nM, and 13 nM, respectively. SGC-SMARCA-BRDVIII also inhibits PB1(2) and PB1(3) , with K d s of 3.7 and 2.0 μM, respectively. SGC-SMARCA-BRDVIII can

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥99%

Nombres e identificadores

Sonrisas canónicas

O=C(N1CCN(CC1)C2=C(N)N=NC(C3=CC=CC=C3O)=C2)OC(C)(C)C

Peso molecular

371.43

Propiedades químicas y físicas

• Solubilidad: DMSO : 25 mg/mL (67.31 mM; ultrasonic and warming and heat to 60°C)