SJ10542 - ≥99% , CAS No.S658806

CAS: S658806 Cat. No.: S658806 Fórmula: C₄₁H₄₆N₁₂O₅S Peso molecular: 818.95

CALIDAD & PUREZA ≥99%

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Application

PROTAC

Descripción general

SJ10542 is a potent and selective JAK2/3 directing phenyl glutarimide (PG)-PROTAC with DC 50 s of 14, 11, and 24 nM for JAK2 , JAK3 , and JAK2-fusion ALL, respectively. SJ10542 utilizes a PG ligand as the cereblon (CRBN) recruiter.

Appearance:Solid

IC50& Target:JAK2 14 nM (DC 50 ) JAK3 11 nM (DC 50 ) JAK2-fusion ALL 24 nM (DC 50 ) Cereblon

Biological Activity:SJ10542 is a potent and selective JAK2/3 directing phenyl glutarimide (PG)-PROTAC with DC 50 s of 14, 11, and 24 nM for JAK2 , JAK3 , and JAK2-fusion ALL, respectively. SJ10542 utilizes a PG ligand as the cereblon (CRBN) recruiter.

Especificaciones

Especificaciones y pureza

≥99%

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C,Desiccated

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥99%

Nombres e identificadores

Peso molecular

818.95

Propiedades químicas y físicas

• Solubilidad: DMSO : 46.67 mg/mL (56.99 mM; Need ultrasonic)

Preguntas frecuentes

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is S658806, the molecular formula is C41H46N12O5S, and the molecular weight is 818.95 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.