Sparfloxacin - Moligand™, 10mM in DMSO , CAS No.110871-86-8

CAS: 110871-86-8 Cat. No.: S408957 Fórmula: C19H22F2N4O3 Peso molecular: 392.4 Beilstein Registry Number: 9170271 Número EC: 629-019-8 PubChem CID: 60464
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
AT-4140, CI-978, PD 131501 | rel-5-​amino-​1-​cyclopropyl-​7-​[(3R,​5S)​-​3,​5-​dimethyl-​1-​piperazinyl]​-​6,​8-​difluoro-​1,​4-​dihydro-​4-​oxo-3-​quinolinecarboxylic acid
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
Size
Alemania (EU)
USA*
Price
Qty
1ml
S408957-1ml
1 Disponible

83,22€

121,40€
Guardar 38,18 € (31.45%)
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 19 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

Sparfloxacin (AT-4140, CI-978, PD 131501) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.
In vitro


In vivo

Sparfloxacin showed good oral efficacy against systemic infections with Staphylococcus aureus , Streptococcus pyogenes , Streptococcus pneumoniae , Escherichia coli , and Pseudomonas aeruginosa in mice.
Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Sinónimos
AT-4140, CI-978, PD 131501 | rel-5-​amino-​1-​cyclopropyl-​7-​[(3R,​5S)​-​3,​5-​dimethyl-​1-​piperazinyl]​-​6,​8-​difluoro-​1,​4-​dihydro-​4-​oxo-3-​quinolinecarboxylic acid
Especificaciones y pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Sparfloxacin (AT-4140, CI-978, PD 131501) is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Propiedades del producto
ALogP0.1
Nombres e identificadores
Isómeros SMILES C[C@@H]1CN(C[C@@H](N1)C)C2=C(C(=C3C(=C2F)N(C=C(C3=O)C(=O)O)C4CC4)N)F
WGK Alemania 2
RTECS VB1986500
PubChem CID 60464
Peso molecular 392.4
Beilstein 9170271

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Punto de inflamación (°F)230°F
Punto de inflamación (°C)>110°C
Punto de ebullición (°C)640℃
Punto de fusión (°C)265°C
Citations of This Product
Referencias
1. Wang Jiarui, Feng Juanjuan, Sun Min, Lian Yujing, Wang Minglin, Qiao Luqin.  (2022)  Sulfonic acid-functionalized covalent organic frameworks as the coating for stir bar sorptive extraction of fluoroquinolones in milk samples.  MICROCHIMICA ACTA,  190  (1): (1-9).  [PMID:36469152] [10.1007/s00604-022-05534-9]
2. Jia-Yu Zeng, Yu-Qi Liang, Yan-Ni Wu, Xiao-Yi Wu, Jia-Ping Lai, Hui Sun.  (2022)  Synthesis and application of novel N, Si-carbon dots for the ratiometric fluorescent monitoring of the antibiotic balofloxacin in tablets and serum.  RSC Advances,  12  (45): (29585-29594).  [PMID:36320748] [10.1039/D2RA02932D]
3. Zhenyu Lu, Gongke Li, Yufei Hu.  (2022)  A Tb3+ functionalized triazine-porous organic framework as a ratiometric fluorescent sensor for determination of ciprofloxacin in aquatic products.  NEW JOURNAL OF CHEMISTRY,  46  (40): (19153-19160).  [PMID:] [10.1039/D2NJ03657F]
4. Jin'ai Chen, Yuting Jin, Taotao Ren, Shuo Wang, Xianghong Wang, Fuyuan Zhang, Yiwei Tang.  (2022)  A novel terbium (III) and aptamer-based probe for label-free detection of three fluoroquinolones in honey and water samples.  FOOD CHEMISTRY,      [PMID:35334319] [10.1016/j.foodchem.2022.132751]
5. Liang Yu-Qi, Wu Xiao-Yi, Zeng Jia-Yu, Wu Yan-Ni, Lai Jia-Ping, Sun Hui.  (2022)  A novel fluorescence ratio probe based on dual-emission carbon dots for highly selective and sensitive detection of chlortetracycline and cell imaging.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  414  (9): (3043-3055).  [PMID:35195741] [10.1007/s00216-022-03908-9]
6. Jin Yuting, Yan Rongfang, Wang Shuo, Wang Xianghong, Zhang Xuemei, Tang Yiwei.  (2022)  Dipeptide nanoparticle and aptamer-based hybrid fluorescence platform for enrofloxacin determination.  MICROCHIMICA ACTA,  189  (3): (1-8).  [PMID:35147788] [10.1007/s00604-022-05182-z]
7. Xiaojun Dai, Yanfei Wu, Zhuanhong Jia, Chunmiao Bo.  (2021)  Preparation of water-compatible magnetic imprinted nanospheres using heptakis (β-cyclodextrin-ionic liquid) as functional monomer for selective recognition of fluoroquinolones in water samples.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2021.106793]
8. Qi Xue, Cong Wang, Yao Lin, Ting-Fu Jiang, Zhihua Lv.  (2021)  Determination of fluoroquinolones illegally added in traditional prostate medicines by ultrasonic-assisted dispersive liquid liquid micro-extraction based on deep eutectic solvent combined with quantitative 19F nuclear magnetic resonance method.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2021.106725]
9. Gongxi Qiao, Gui Chen, Qin Wen, Wanqiang Liu, Jinwei Gao, Zhiqiang Yu, Qianming Wang.  (2020)  Rapid conversion from common precursors to carbon dots in large scale: Spectral controls, optical sensing, cellular imaging and LEDs application.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:32682119] [10.1016/j.jcis.2020.07.034]
10. Kaili Yu, Mei-E. Yue, Jie Xu, Ting-Fu Jiang.  (2020)  Determination of fluoroquinolones in milk, honey and water samples by salting out-assisted dispersive liquid-liquid microextraction based on deep eutectic solvent combined with MECC.  FOOD CHEMISTRY,      [PMID:32622188] [10.1016/j.foodchem.2020.127371]
11. Shuai Han, Liang Yang, Zhigang Wen, Suyun Chu, Mei Wang, Zhenyang Wang, Changlong Jiang.  (2020)  A dual-response ratiometric fluorescent sensor by europium-doped CdTe quantum dots for visual and colorimetric detection of tetracycline.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:32768819] [10.1016/j.jhazmat.2020.122894]
12. Zhi Shen, Cheng Zhang, Xinling Yu, Jian Li, Zhenyang Wang, Zhongping Zhang, Bianhua Liu.  (2018)  Microwave-assisted synthesis of cyclen functional carbon dots to construct a ratiometric fluorescent probe for tetracycline detection.  Journal of Materials Chemistry C,  (36): (9636-9641).  [PMID:] [10.1039/C8TC02982B]
13. Suyu Ren, Jing Tao, Feng Tan, Ying Cui, Xiaona Li, Jingwen Chen, Xin He, Yi Wang.  (2018)  Diffusive gradients in thin films based on MOF-derived porous carbon binding gel for in-situ measurement of antibiotics in waters.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:30029123] [10.1016/j.scitotenv.2018.07.013]
14. Wang Nan, Wang Yan-Fei, Omer Ahmed M., Ouyang Xiao-kun.  (2017)  Fabrication of novel surface-imprinted magnetic graphene oxide-grafted cellulose nanocrystals for selective extraction and fast adsorption of fluoroquinolones from water.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  409  (28): (6643-6653).  [PMID:28940000] [10.1007/s00216-017-0619-9]
15. Yan-Fei Wang, Yang-Guang Wang, Xiao-Kun Ouyang, Li-Ye Yang.  (2017)  Surface-Imprinted Magnetic Carboxylated Cellulose Nanocrystals for the Highly Selective Extraction of Six Fluoroquinolones from Egg Samples.  ACS Applied Materials & Interfaces,      [PMID:28005332] [10.1021/acsami.6b12206]
16. Ruijie Tang, Lingfei Li, Yaowei Zhu, Minghui Zhan, Jun Zhao, Changlong Jiang, Bianhua Liu.  (2025)  Ratiometric fluorescent sensor for sensitive visualization of full-spectrum fluoroquinolone antibiotic residues in the environment.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.113260]
17. Tianci Lv, Fubin Liu, Mengqian Xiao, Ying Liu, Litao Wang, Guihua Gao.  (2024)  Synthesis of reusable hierarchical Pore PVDF-MIL-101(Cr) foam for Solid phase extraction of fluoroquinolones from water and its adsorption behavior for anionic and cationic dyes.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:39637615] [10.1016/j.chroma.2024.465577]
18. Huang Xiao-Qing, Wang Mao-Yu, Wang Xiao-Chen, Shi Xin, Li Rui-Wen, Wu Shuang, Li Ying.  (2025)  A surface-imprinting lanthanide fluorescent hybrid probe on SiO2 microspheres for the detection of enrofloxacin.  MICROCHIMICA ACTA,  192  (8): (1-12).  [PMID:40731103] [10.1007/s00604-025-07369-6]
19. Zhiwen Li, Jiyue Zhang, Qiyao Sun, Wenwen Shi, Tingxian Tao, Yingqiang Fu.  (2022)  Moxifloxacin detection based on fluorescence resonance energy transfer from carbon quantum dots to moxifloxacin using a ratiometric fluorescence probe.  NEW JOURNAL OF CHEMISTRY,  46  (9): (4226-4232).  [PMID:] [10.1039/D1NJ05961K]
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