SR-717 lithium - 10mM in DMSO , CAS No.2375421-09-1

CAS: 2375421-09-1 Cat. No.: S422788 Fórmula: C15H8F2LiN5O3 Peso molecular: 351.19 PubChem CID: 139434658
Disponible para pedir
GRADE & PURITY 10mM in DMSO
Synonyms
Benzoic acid,4,​5-​difluoro-​2-​[[[6-​(1H-​imidazol-​1-​yl)​-​3-​pyridazinyl]​carbonyl]​amino]​-​,lithium salt (1:1)
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
★
Size
Alemania (EU)
USA*
Price
Qty
1ml
S422788-1ml
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2 Disponible

148,30€

174,33€
Guardar 26,03 € (14.93%)
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

SR-717 lithium SR-717 lithium is a non-nucleotide STING agonist that demonstrates broad interspecies and interallelic specificity with EC50 of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 (cGAS KO) cell lines, respectively. SR-717 lithium also induces the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. SR-717 lithium exhibits antitumor activity.

Targets

STING (in ISG-THP1 (WT) cells); STING (in ISG-THP1 (cGAS KO) cells) 2.1 μM(EC50); 2.2 μM(EC50)

Specifications

Sinónimos
Benzoic acid,4,​5-​difluoro-​2-​[[[6-​(1H-​imidazol-​1-​yl)​-​3-​pyridazinyl]​carbonyl]​amino]​-​,lithium salt (1:1)
Especificaciones y pureza
10mM in DMSO
Mecanismos bioquímicos y fisiológicos
SR-717 lithium is a non-nucleotide STING agonist that demonstrates broad interspecies and interallelic specificity with EC50 of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 (cGAS KO) cell lines, respectively. SR-717 lithium also induces the expression
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Propiedades del producto
ALogP
1.765
Recuento HBD
1
Enlace rotable
5
Nombres e identificadores
Pubchem Sid
Sonrisas canónicas
[Li+].C1=CC(=NN=C1C(=O)NC2=CC(=C(C=C2C(=O)[O-])F)F)N3C=CN=C3
IUPAC Name
lithium;4,5-difluoro-2-[(6-imidazol-1-ylpyridazine-3-carbonyl)amino]benzoate
InChIKey
ODSAJRWPLSVEHJ-UHFFFAOYSA-M
INCHI
1S/C15H9F2N5O3.Li/c16-9-5-8(15(24)25)12(6-10(9)17)19-14(23)11-1-2-13(21-20-11)22-4-3-18-7-22;/h1-7H,(H,19,23)(H,24,25);/q;+1/p-1
PubChem CID
139434658
Peso molecular
351.19

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClaseBenzene and substituted derivatives
SubclassAnilides
Intermediate Tree Nodes Not available
Direct ParentAromatic anilides
Alternative Parents Halobenzoic acids  4-halobenzoic acids  3-halobenzoic acids  Benzoic acids  Benzoyl derivatives  Fluorobenzenes  Pyridazines and derivatives  Fatty acids and conjugates  Vinylogous amides  Heteroaromatic compounds  Azoles  Carboxylic acid salts  Organic metal halides  Organic lithium salts  Monocarboxylic acids and derivatives  Carboxylic acids  Carboxylic acid amides  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Organonitrogen compounds  Organofluorides  Organic zwitterions  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Aromatic anilide - Halobenzoic acid - 4-halobenzoic acid - 3-halobenzoic acid - Halobenzoic acid or derivatives - 4-halobenzoic acid or derivatives - 3-halobenzoic acid or derivatives - Benzoic acid - Benzoic acid or derivatives - Benzoyl - Halobenzene - Fluorobenzene - Fatty acid - Pyridazine - Heteroaromatic compound - Vinylogous amide - Azole - Carboxylic acid salt - Carboxamide group - Organic metal halide - Organic lithium salt - Azacycle - Organic alkali metal salt - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organic salt - Organic zwitterion - Organooxygen compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Aromatic heteromonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as aromatic anilides. These are aromatic compounds containing an anilide group in which the carboxamide group is substituted with an aromatic group. They have the general structure RNC(=O)R', where R= benzene, and R = aryl group.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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1 results found

Lot NumberCertificate TypeFechaArticulo
G2410387Certificate of AnalysisMay 13, 2026 S422788
Propiedades químicas y físicas
DMSO (mg/ml) Solubilidad máxima40
DMSO (mM) Solubilidad máxima113.898459523335
Agua (mg/ml) Solubilidad máxima<1
Peso molecular351.200 g/mol
XLogP3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count4
Exact Mass351.076 Da
Monoisotopic Mass351.076 Da
Topological Polar Surface Area113.000 Ų
Heavy Atom Count26
Formal Charge0
Complexity518.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Citations of This Product
Calculadoras de soluciones
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