SRI 31215 TFA - ≥98% , CAS No.1832686-44-8

CAS: 1832686-44-8 Cat. No.: S412134 Fórmula: C₂₇H₃₄F₃N₅O₃ Peso molecular: 533.59 PubChem CID: 102004307

GRADE & PURITY ≥98%

Synonyms

SRI 31215

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

SRI 31215, a small molecule that acts as a triplex inhibitor of matriptase, hepsin and HGFA and mimics the activity of HAI-1/2, endogenous inhibitors of HGF activation with IC50s of 0.69 μM, 0.65 μM, 0.3 μM.

Specifications

Sinónimos

SRI 31215

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

SRI 31215 (TFA) is a triplex inhibitor of matriptase, hepsin and hepatocyte growth factor activator (HGFA) with IC50 of 0.69 μM, 0.65 μM, 0.3 μM, respectively. SRI 31215 blocks pro-HGF activation and thus mimics the activity of HAI-1/2.

Condiciones de almacenamiento de almacenamiento

Store at -20°C,Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Nombres e identificadores

Pubchem Sid

528767194

Sonrisas canónicas

CC1CN(C(=O)N(C1)C2=CC=CC(=C2)C(=N)N)CC3CCN(CC3)CC4=CC=CC=C4.C(=O)(C(F)(F)F)O

IUPAC Name

3-[3-[(1-benzylpiperidin-4-yl)methyl]-5-methyl-2-oxo-1,3-diazinan-1-yl]benzenecarboximidamide;2,2,2-trifluoroacetic acid

InChIKey

QJFJKJLPPLYFJA-UHFFFAOYSA-N

INCHI

1S/C25H33N5O.C2HF3O2/c1-19-15-29(25(31)30(16-19)23-9-5-8-22(14-23)24(26)27)18-21-10-12-28(13-11-21)17-20-6-3-2-4-7-20;3-2(4,5)1(6)7/h2-9,14,19,21H,10-13,15-18H2,1H3,(H3,26,27);(H,6,7)

Isómeros SMILES

CC1CN(C(=O)N(C1)C2=CC=CC(=C2)C(=N)N)CC3CCN(CC3)CC4=CC=CC=C4.C(=O)(C(F)(F)F)O

PubChem CID

102004307

Peso molecular

533.59

Mecanismos de acción

Propiedades químicas y físicas

• Sensibilidad: Moisture sensitive