Sulfathiazole - 10mM in DMSO , CAS No.72-14-0

CAS: 72-14-0 Cat. No.: S408472 Fórmula: C₉H₉N₃O₂S₂ Peso molecular: 255.32 Beilstein Registry Number: 226178 Número EC: 200-771-5 PubChem CID: 5340

GRADE & PURITY 10mM in DMSO

Synonyms

4-amino-N-(thiazol-2-yl)benzenesulfonamide

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.
In vitro

Sulfathiazole (20 μg/L) starts to be degraded between day 31 and day 38 in one of the two batch reactors containing different wastewater matrices. Sulfathiazole is degraded at a substantially faster rate than sulfamethoxazole or sulfamethazine in the nitrification process (S3). Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole has acidity constant of pKa of 7.1and retention times (tR) of 7.8. S/N values for Sulfathiazole are above 100 at the 1 mg/kg level. Sulfathiazole sorption to inorganic sorbents exhibits pronounced pH dependence consistent with sorbate speciation and sorbent charge properties. Sulfathiazole cations are most important for sorption to clay minerals, followed by neutral species. Sulfathiazole posseses at least five crystalline or polymorphic forms: I, II, III, IV and V. Although both amido and imido forms are possible for the sulfathiazole molecule, the Sulfathiazole exists in the solid state in the imido form. Sulfathiazole (94.9 mg/L) causes a significant increase in reactive oxygen species (ROS) generation and lipid peroxidation in the presence of ultraviolet B (UV-B) light. Exposure to Sulfathiazole and UV-B light causes apparent up-regulation of alpha-esterase, hemoglobin, and vitellogenin mRNA and significantly affect the survival of daphnids.

In vivo

Cell Data

cell lines：Colo205, H1755, H1395, H1666, A549, H157, and H1703 cells

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

4-amino-N-(thiazol-2-yl)benzenesulfonamide

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

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Propiedades del producto

ALogP

0.1

Nombres e identificadores

Isómeros SMILES

C1=CC(=CC=C1N)S(=O)(=O)NC2=NC=CS2

WGK Alemania

2

RTECS

WP2360000

PubChem CID

5340

Peso molecular

255.32

Beilstein

226178

Propiedades químicas y físicas

• Punto de fusión (°C): 200-202°C

Preguntas frecuentes

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 72-14-0, the molecular formula is C9H9N3O2S2, and the molecular weight is 255.32 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.