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ERCC4

DescripciónDNA repair endonuclease XPF

Gene and Protein Information

Gene ID2072
Uniprot Accession IDs Q92889 A5PKV6 A8K111 O00140 Q8TD83
Ensembl ID ENSP00000310520
Symbol ERCC11 XPF XPF RAD1 FANCQ XFEPS ERCC11
FamilyBelongs to the XPF family.
Sequence
MESGQPARRIAMAPLLEYERQLVLELLDTDGLVVCARGLGADRLLYHFLQLHCHPACLVLVLNTQPAEEEYFINQLKIEGVEHLPRRVTNEITSNSRYEVYTQGGVIFATSRILVVDFLTDRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVRKLYLWPRFHVAVNSFLEQHKPEVVEIHVSMTPTMLAIQTAILDILNACLKELKCHNPSLEVEDLSLENAIGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEKAFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEEFDVNLSSDAAFGILKEPLTIIHPLLGCSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASRPGKPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLVRGTASADVSTDTRKAGGQEQNGTQQSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPEMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLTSRGALFQEISSNDISSKLTLLTLHFPRLRILWCPSPHATAELFEELKQSKPQPDAATALAITADSETLPESEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNIAELAALSQDELTSILGNAANAKQLYDFIHTSFAEVVSKGKGKK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNombreNIFOther Gene IDSources
Chimp453935ERCC4ERCC excision repair 4, endonuclease catalytic subunit9598VGNC:9004OMA, EggNOG
Macaque712641ERCC4ERCC excision repair 4, endonuclease catalytic subunit9544Inparanoid, OMA, EggNOG
Mouse50505Ercc4excision repair cross-complementing rodent repair deficiency, complementation group 410090MGI:1354163Inparanoid, OMA, EggNOG
RatAABR07029002.2-10116OMA, EggNOG
Dog479842ERCC4ERCC excision repair 4, endonuclease catalytic subunit9615VGNC:40444Inparanoid, OMA, EggNOG
Horse100050812ERCC4ERCC excision repair 4, endonuclease catalytic subunit9796VGNC:51128Inparanoid, OMA, EggNOG
Cow516371ERCC4ERCC excision repair 4, endonuclease catalytic subunit9913VGNC:28571Inparanoid, OMA, EggNOG
Pig100516427ERCC4ERCC excision repair 4, endonuclease catalytic subunit9823Inparanoid, OMA, EggNOG
Opossum100024202ERCC4ERCC excision repair 4, endonuclease catalytic subunit13616Inparanoid, OMA, EggNOG
Chicken416420ERCC4ERCC excision repair 4, endonuclease catalytic subunit9031CGNC:2155Inparanoid, OMA, EggNOG
Anole lizard100567423ercc4ERCC excision repair 4, endonuclease catalytic subunit28377Inparanoid, OMA, EggNOG
Xenopus100145552ercc4excision repair cross-complementation group 48364XB-GENE-986815Inparanoid, OMA, EggNOG
Zebrafish327322ercc4excision repair cross-complementation group 47955ZDB-GENE-030131-5533Inparanoid, OMA, EggNOG
Fruitfly31373mei-9meiotic 97227FBgn0002707Inparanoid, EggNOG
S.cerevisiae856085RAD1ssDNA endodeoxyribonuclease RAD14932S000005943Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    DNA binding protein    /    DNA repair endonuclease XPF
protein    /    nucleic acid binding    /    nuclease    /    DNA repair endonuclease XPF
protein    /    nucleic acid binding    /    endodeoxyribonuclease    /    DNA repair endonuclease XPF
DTO Classes
protein    /    Enzyme    /    Nuclease    /    Endodeoxyribonuclease    /    DNA repair endonuclease XPF

Associated Recombinant Proteins

NombreSpecification and purityExpression systemProtein labelDisponibilidadMostrar detalles

Associated Antibodies

NombreSpecificationsSpecies reactivityAplicaciónDisponibilidadMostrar detalles

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NombreDirect Associated TargetsDisease TypeMondoid

      Bibliography

      🔙[Back to Target (Human)]
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