TPCK - Moligand™, 10 mM in DMSO , CAS No.402-71-1

CAS: 402-71-1 Cat. No.: T1495595 Fórmula: C₁₇H₁₈ClNO₃S Peso molecular: 351.85 Beilstein Registry Number: 2895215 Número EC: 206-954-6

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

TPCK (L-1-Tosylamido-2-phenylethyl chloromethyl ketone; L-TPCK) is an effective serine protease inhibitor and also a blocker of the PDK1/Akt pathway. TPCK can modify the E7 protein in actively keratinocyte cells. TPCK can induce cellular apoptosis , suppress tumor growth, reduce hypoxic-ischemic brain injury in rat pups, and affect vascular permeability in inflamed rats.

Specifications

Especificaciones y pureza

Moligand™, 10 mM in DMSO

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Nombres e identificadores

• Isómeros SMILES: CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](CC2=CC=CC=C2)C(=O)CCl
• RTECS: XT5613500
• Peso molecular: 351.85
• Beilstein: 2895215
• Reaxy-Rn: 2895215
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2895215&ln=

Propiedades químicas y físicas

• Rotación específica [α]: -87.0 to -91.0 deg(C=1, EtOH)
• Punto de fusión (°C): 106.0 to 110.0 °C

Referencias

1. Yi-ni Lu, Xiao-han Wang, Bo-cheng Xu, Yufen Zheng, Xiong Zhang, Yi Liu, Tian-yin Wang, Feng Yu.  (2025)  Urinary Trypsin Inhibitor Exerts Multifaceted Regulation of Angiopoietin 2 in Septic Cardiomyopathy.  EUROPEAN JOURNAL OF PHARMACOLOGY,      [PMID:40651788] [10.1016/j.ejphar.2025.177944]

Preguntas frecuentes

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 402-71-1, the molecular formula is C17H18ClNO3S, and the molecular weight is 351.85 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.