Valproic acid-d15 - ≥99%,≥99 atom% D , CAS No.362049-65-8

CAS: 362049-65-8 Cat. No.: V650220 Fórmula: C₈HD₁₅O₂ Peso molecular: 159.30

GRADE & PURITY ≥99%,≥99 atom% D

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Valproic acid-d15 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.

Specifications

Especificaciones y pureza

≥99%,≥99 atom% D

Mecanismos bioquímicos y fisiológicos

Valproic acid-d 15 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor , with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2 . Valpro

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥99%,≥99 atom% D

Nombres e identificadores

• Pubchem Sid: 528767684
• Isómeros SMILES: [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])(C(=O)O)C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
• CAS alternativo: 99-66-1(unlabelled)
• Peso molecular: 159.30