2-Chloroadenosine - Moligand™, 10 mM in DMSO , CAS No.146-77-0

CAS: 146-77-0 Cat. No.: C1500268 Formula: C₁₀H₁₂ClN₅O₄ Peso molecolare: 301.69 Beilstein Registry Number: 43957 Numero EC: 205-678-3

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

2-Chloroadenosine, a stable adenosine analogue, protects against long term development of ischaemic cell loss in the rat hippocampus. 2-Chloroadenosine is an apparent competitive inhibitor of uridine influx (apparent K i =33 μM) and high-affinity nitrobenzylthioinosine binding (apparent K i =0.18 mM). 2-Chloroadenosine is a transported permeant for the nucleoside transporter in human erythrocytes .

Specifications

Specifiche e purezza

Moligand™, 10 mM in DMSO

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Nomi e identificatori

• Isomeri SMILES: C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)Cl)N
• WGK Germania: 3
• RTECS: AU7357550
• Peso molecolare: 301.69
• Beilstein: 43957
• Reaxy-Rn: 23207945
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=23207945&ln=

Proprietà chimiche e fisiche

• Rotazione specifica [α]: [α]D -50° (C=0.1,H2O)
• Punto di fusione (°C): 162 °C

Riferimenti

1. Guangrong Sun, Pei Guo, Han Yeong Kaw, Meijiao Zhou, Wei Wang.  (2023)  Uncovering an Emerging Group of Halogenated Nucleobase-Derived Disinfection Byproducts in Drinking Water: Prioritization of the Highly Cytotoxic 2-Chloroadenine.  ENVIRONMENTAL SCIENCE & TECHNOLOGY,      [PMID:37232460] [10.1021/acs.est.3c01484]

2. Guangrong Sun, Pei Guo, Rong Liu, Han Yeong Kaw, Wei Wang.  (2025)  Fragmentation pattern-based nontargeted screening strategy uncovered novel halogenated nucleotides in drinking water.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:40037189] [10.1016/j.jhazmat.2025.137797]

3. Jiaying Long, Yicong Zhang, Mengxing Zhang, Zhenkang Diao, Taotian Zhang, Hanming Zhang, Qing Lin, Tao Gong, Xun Sun, Zhirong Zhang, Shiqi Huang, Ling Zhang.  (2025)  Delivery of NK cells in an injectable dynamic hydrogel effectively remodels tumor microenvironment and inhibits post-surgery tumor recurrence.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.163507]

Domande frequenti

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 146-77-0, the molecular formula is C10H12ClN5O4, and the molecular weight is 301.69 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.