6-Thio-GTP (aqueous solution) (Thiogtp) - ≥95% , CAS No.17670-19-8

CAS: 17670-19-8 Cat. No.: T276292 Formula: C₁₀H₁₆N₅O₁₃P₃S Peso molecolare: 539.25 PubChem CID: 3036888

GRADE & PURITY ≥95%

Synonyms

6-Thioguanosine-5'-O-triphosphate sodium salt | 6-Thioguanosine 5'-triphosphate | 6-T-GTP | Thiogtp | [[(2R,3S,4R,5S)-5-(2-amino-6-sulfanylidene-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate | 6-Thioguanos

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Panoramica

Store at -20°C (desiccating conditions).

Specifications

Sinonimi

6-Thioguanosine-5'-O-triphosphate sodium salt | 6-Thioguanosine 5'-triphosphate | 6-T-GTP | Thiogtp | [[(2R,3S,4R,5S)-5-(2-amino-6-sulfanylidene-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate | 6-Thioguanos

Specifiche e purezza

≥95%

Meccanismi biochimici e fisiologici

Vac-1-Rac signaling inhibitor. Azathioprine metabolite. 6-mercaptopurine derivative. Inhibits TNF-α-induced downstream signaling via JNK. Reduces c-Jun, transcription factor-2 and NF-κB activation. Shows immunosuppressant effects

Condizioni di conservazione di stoccaggio

Store at -20°C,Desiccated

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Tipo di azione

INHIBITOR

Nota

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purezza

≥95%

Nomi e identificatori

Sorrisi canonici

C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)NC(=NC2=S)N

IUPAC Name

[[(2R,3S,4R,5S)-5-(2-amino-6-sulfanylidene-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

InChIKey

QENYANNAQSWPLM-BDXYJKHTSA-N

INCHI

1S/C10H16N5O13P3S/c11-10-13-7-4(8(32)14-10)12-2-15(7)9-6(17)5(16)3(26-9)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-3,5-6,9,16-17H,1H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,32)/t3-,5-,6-,9+/m1/s1

Isomeri SMILES

C1=NC2=C(N1[C@@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)NC(=NC2=S)N

PubChem CID

3036888

Peso molecolare

539.25

Proprietà chimiche e fisiche

• Solubilità: Supplied in water (10 mM)

Domande frequenti

What is the purity of this product?

This product is supplied at ≥95% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 17670-19-8, the molecular formula is C10H16N5O13P3S, and the molecular weight is 539.25 g/mol. InChIKey QENYANNAQSWPLM-BDXYJKHTSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.