≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
BCH001 BCH001 is a specific PAPD5 inhibitor that restores telomerase activity and telomere length in dyskeratosis congenita (DC) patient induced pluripotent stem cells. PAPD5 is a noncanonical poly(A) polymerase with an unusual RNA-binding motif.
Targets
PAPD5
In vitro
BCH001 is a specific PAPD5 inhibitor that restores telomerase activity and telomere length in DC patient induced pluripotent stem cells.
Cell Research(from reference)
Cell lines：CD34+ HSPCs, iPSCs and fibroblasts
Concentrations：1 μM, 5 μM, 100 μM
Incubation Time：72 h, 5 days, 14 days
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Classe | Quinolines and derivatives |
| Subclass | Aminoquinolines and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | 4-aminoquinolines |
| Alternative Parents | Aminobenzoic acids Pyridinecarboxylic acids Benzoic acids Aniline and substituted anilines Benzoyl derivatives Aminopyridines and derivatives Dicarboxylic acids and derivatives Vinylogous amides Heteroaromatic compounds Trihalomethanes Amino acids Carboxylic acid esters Secondary amines Azacyclic compounds Carboxylic acids Alkyl fluorides Organofluorides Organooxygen compounds Organic oxides Hydrocarbon derivatives Organopnictogen compounds |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | 4-aminoquinoline - Aminobenzoic acid - Aminobenzoic acid or derivatives - Benzoic acid or derivatives - Benzoic acid - Pyridine carboxylic acid - Pyridine carboxylic acid or derivatives - Benzoyl - Aniline or substituted anilines - Aminopyridine - Monocyclic benzene moiety - Dicarboxylic acid or derivatives - Pyridine - Benzenoid - Heteroaromatic compound - Vinylogous amide - Amino acid or derivatives - Amino acid - Trihalomethane - Carboxylic acid ester - Azacycle - Secondary amine - Carboxylic acid derivative - Carboxylic acid - Alkyl fluoride - Hydrocarbon derivative - Organohalogen compound - Halomethane - Organofluoride - Organonitrogen compound - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Amine - Alkyl halide - Aromatic heteropolycyclic compound |
| Descrizione | This compound belongs to the class of organic compounds known as 4-aminoquinolines. These are organic compounds containing an amino group attached to the 4-position of a quinoline ring system. |
| External Descriptors | Not available |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Data | Oggetto |
|---|---|---|---|
 J2213323 | Certificate of Analysis | Aug 11, 2022 | B414306 |
| J2213326 | Certificate of Analysis | Aug 11, 2022 | B414306 |
| J2213331 | Certificate of Analysis | Aug 11, 2022 | B414306 |
| J2213425 | Certificate of Analysis | Aug 11, 2022 | B414306 |
| J2213426 | Certificate of Analysis | Aug 11, 2022 | B414306 |
| Solubilità | Solubility (25°C) In vitro DMSO: 84 mg/mL (199.83 mM); Ethanol: 5 mg/mL (11.89 mM); Water: Insoluble; |
|---|---|
| DMSO (mg/mL) Solubilità massima | 84 |
| DMSO (mM) Solubilità massima | 199.83822619784 |
| Acqua (mg/mL) Solubilità massima | ＜1 |
| Peso molecolare | 420.300 g/mol |
| XLogP3 | 5.200 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 7 |
| Exact Mass | 420.093 Da |
| Monoisotopic Mass | 420.093 Da |
| Topological Polar Surface Area | 97.800 Ų |
| Heavy Atom Count | 30 |
| Formal Charge | 0 |
| Complexity | 618.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
