Bestim TFA - ≥98% , CAS No.66471-20-3(free base)

CAS: 66471-20-3(free base) Cat. No.: B769975 Formula: C₁₆H₁₉N₃O₅ Peso molecolare: 333.34（free base）

GRADE & PURITY ≥98%

Synonyms

H-D-Glu(Trp-OH)-OH | γ-Glu-Trp

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Panoramica

Bestim (γ-Glu-Trp) is a dipeptide that exhibits high affinity for rat peritoneal macrophages, thymocytes, and the plasma membranes isolated from these cells, with Kd values of 3.1, 2.1, 18.6, and 16.7 nM respectively. Bestim inhibits adenylate cyclase in the membranes of mouse macrophages and thymocytes. Bestim has immunomodulatory activity.

Sequence Short：{γGlu}-W

Specifications

Sinonimi

H-D-Glu(Trp-OH)-OH | γ-Glu-Trp

Specifiche e purezza

≥98%

Condizioni di conservazione di stoccaggio

Protected from light,Store at -20°C,Argon charged

Spedito in

Ice chest + Ice pads

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Tipo di azione

INHIBITOR

Purezza

≥98%

Nomi e identificatori

• Sorrisi canonici: C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NC(=O)CCC(C(=O)O)N
• IUPAC Name: (2S)-2-amino-5-[[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]amino]-5-oxopentanoic acid
• InChIKey: CATMPQFFVNKDEY-AAEUAGOBSA-N
• INCHI: 1S/C16H19N3O5/c17-11(15(21)22)5-6-14(20)19-13(16(23)24)7-9-8-18-12-4-2-1-3-10(9)12/h1-4,8,11,13,18H,5-7,17H2,(H,19,20)(H,21,22)(H,23,24)/t11-,13-/m0/s1
• Peso molecolare: 333.34（free base）

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Peptides
          • Level6 Dipeptides

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Peptides
• Direct Parent: Dipeptides
• Alternative Parents: Gamma-glutamyl amino acids Glutamine and derivatives N-acyl-L-alpha-amino acids 3-alkylindoles L-alpha-amino acids Substituted pyrroles Benzenoids N-acyl amines Dicarboxylic acids and derivatives Heteroaromatic compounds Amino acids Secondary carboxylic acid amides Carboxylic acids Azacyclic compounds Hydrocarbon derivatives Monoalkylamines Carbonyl compounds Organic oxides
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Alpha-dipeptide - Gamma-glutamyl alpha-amino acid - Glutamine or derivatives - N-acyl-alpha amino acid or derivatives - N-acyl-alpha-amino acid - N-acyl-l-alpha-amino acid - Alpha-amino acid - Alpha-amino acid or derivatives - 3-alkylindole - L-alpha-amino acid - Indole or derivatives - Indole - Fatty acyl - N-acyl-amine - Benzenoid - Substituted pyrrole - Dicarboxylic acid or derivatives - Fatty amide - Heteroaromatic compound - Pyrrole - Amino acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Amino acid - Organoheterocyclic compound - Carboxylic acid - Azacycle - Primary amine - Hydrocarbon derivative - Organic nitrogen compound - Organic oxide - Primary aliphatic amine - Organic oxygen compound - Carbonyl group - Organonitrogen compound - Amine - Organooxygen compound - Aromatic heteropolycyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Sensibilità: Moisture sensitive；Light sensitive
• Peso molecolare: 333.340 g/mol
• XLogP3: -2.700
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 333.132 Da
• Monoisotopic Mass: 333.132 Da
• Topological Polar Surface Area: 146.000 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 484.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1