CVN424 - 10mM in DMSO , CAS No.2254706-21-1

CAS: 2254706-21-1 Cat. No.: C656045 Formula: C₂₄H₂₉F₂N₅O₃ Peso molecolare: 473.52 Numero EC: 192-146-8 PubChem CID: 137359492

QUALITÀ & PUREZZA 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

CVN424 is an orally active and selective GPR6 inverse agonist with a K i of 9.4 nM and an EC 50 of 38 nM. CVN424 is brain-penetrant and has the potential for Parkinson disease research

In Vitro

CVN424 (Compound 6i) has 265 fold and 68 fold selectivities over GPR3 and GPR12. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:Ki: 9.4 nM (GPR6), EC50: 38 nM (GPR6)

Specifiche

Specifiche e purezza

10mM in DMSO

Meccanismi biochimici e fisiologici

CVN424 is an orally active and selective GPR6 inverse agonist with a K i of 9.4 nM and an EC 50 of 38 nM. CVN424 is brain-penetrant and has the potential for Parkinson disease research.

Condizioni di conservazione di stoccaggio

Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nomi e identificatori

Isomeri SMILES

CC(=O)N1CCC2=C(C1)N=C(C(=N2)N3CCC(CC3)OC4=C(C=C(C=C4)F)F)N[C@@H]5CCOC5

CAS alternativo

2254706-21-1

PubChem CID

137359492

Peso molecolare

473.52

Obiettivi associati (umani)

GPR6 Tchem G-protein coupled receptor 6 (4 Activities)

Discover Target: GPR6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (2 Activities)

Discover Target: KCNH2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)