Denatonium benzoate(THS 839) - Moligand™, 10 mM in DMSO , CAS No.3734-33-6

CAS: 3734-33-6 Cat. No.: D1499493 Formula: C₂₁H₂₉N₂O·C₇H₅O₂ Peso molecolare: 446.58 Beilstein Registry Number: 8179408 Numero EC: 223-095-2

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

Denatonium benzoate (THS-839) is known as the most bitter compound and is commonly used as a deterrent (bittering agent) to activate different types of bitter taste receptors ( TAS2Rs ) with oral activity. Denatonium benzoate can enhance insulin secretion, has anti-inflammatory effects, and promotes allergy susceptibility .

Specifications

Specifiche e purezza

Moligand™, 10 mM in DMSO

Condizioni di conservazione di stoccaggio

Desiccated,Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Tipo di azione

ACTIVATOR

Nomi e identificatori

• Isomeri SMILES: CC[N+](CC)(CC1=CC=CC=C1)CC(=O)NC2=C(C=CC=C2C)C.C1=CC=C(C=C1)C(=O)[O-]
• WGK Germania: 2
• RTECS: BO6650000
• Peso molecolare: 446.58
• Beilstein: 8179408
• Reaxy-Rn: 8179408
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8179408&ln=

Proprietà chimiche e fisiche

• Punto di infiammabilità (°F): 212 °F
• Punto di infiammabilità (°C): 100 °C
• Punto di fusione (°C): 160.0 to 164.0 °C

Riferimenti

1. Liwei Zhang, Huiwen Sun, Ewald Grosse-Wilde, Long Zhang, Bill S. Hansson, Hany K.M. Dweck.  (2023)  Cross-generation pheromonal communication drives Drosophila oviposition site choice.  CURRENT BIOLOGY,      [PMID:37098339] [10.1016/j.cub.2023.03.090]

2. Guocai Liu, Wei Wen, Zhiyuan Zhao, Xin Huang, Yifan Li, Mingcong Qin, Zhichao Pan, Yunlong Guo, Yunqi Liu.  (2023)  Bionic Tactile-Gustatory Receptor for Object Identification Based on All-Polymer Electrochemical Transistor.  ADVANCED MATERIALS,  35  (24): (2300242).  [PMID:37025036] [10.1002/adma.202300242]

3. Jun Yang, Hao Guo, Nan-Ji Jiang, Rui Tang, Guo-Cheng Li, Ling-Qiao Huang, Joop J. A. van Loon, Chen-Zhu Wang.  (2021)  Identification of a gustatory receptor tuned to sinigrin in the cabbage butterfly Pieris rapae.  PLoS Genetics,  17  (7): (e1009527).  [PMID:34264948] [10.1371/journal.pgen.1009527]

4. Kai Ni, Bo Che, Rong Gu, Chunhong Wang, Hongyang Xu, Huiduo Li, Shiyan Cen, Mingzhi Luo, Linhong Deng.  (2024)  BitterDB database analysis plus cell stiffness screening identify flufenamic acid as the most potent TAS2R14-based relaxant of airway smooth muscle cells for therapeutic bronchodilation.  Theranostics,      [PMID:38389834] [10.7150/thno.92492]

Domande frequenti

How should this product be stored?

Store at ?80 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 3734-33-6, the molecular formula is C28H34N2O3, and the molecular weight is 446.58 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.