Antipsychotics and Antidepressants

Aladdin provides a wide selection of bioactive antipsychotic and antidepressant compounds for use in research models. Many of these agents influence dopamine signaling by blocking one or more dopamine receptor subtypes or inhibiting dopamine transporters. Our catalog includes first-generation (typical) antipsychotics such as Chlorpromazine Hydrochloride (C131611 C129569) and Haloperidol (H113852), as well as second-generation (atypical) antipsychotics including Clozapine (C126883) and Risperidone (R127644).

Another important category in our neuroactive compound offerings consists of antidepressants, which generally act to prolong neurotransmitter activity in the brain. These compounds frequently target serotonin receptors, dopamine receptors, ion channels, or neurotransmitter transporters. Selective serotonin reuptake inhibitors (SSRIs) work by preventing the presynaptic reuptake of serotonin into neurons, thereby increasing its availability to interact with serotonin receptors. Fluoxetine Hydrochloride (F131623) and Paroxetine Hydrochloride Hemihydrate (P129711) are two SSRIs widely used in research applications.

Monoamine oxidase inhibitors (MAOIs) represent another class of antidepressants. These agents inhibit monoamine oxidase, an enzyme responsible for breaking down serotonin and dopamine. By blocking this enzyme, MAOIs raise neurotransmitter levels, enabling greater receptor activation and supporting signal transmission involved in reward, reinforcement, learning, and memory. Aladdin carries several MAOIs, including Tranylcypromine Hydrochloride (R132818) and Moclobemide (M118359).

A more comprehensive selection of representative antipsychotic and antidepressant compounds from our product library is available in the listing below.

Aladdin catalog	Product name	Aladdin catalog	Product name
A129432	Amisulpride	K129651	Ketanserin
A129730	Amitriptyline Hydrochloride	M129850	Maprotiline HCl
A129596	Amoxapine	M276228	Melitracen Hydrochloride
A124880	Aripiprazole	M304141	Mirtazapine
A129598	Azaperone	N159830	Nefazodone Hydrochloride
B129446	Bupropion Hydrochloride	O126519	Olanzapine
B129462	Buspirone Hydrochloride	P120141	Paliperidone
C122737	Citalopram Hydrobromide	Q129431	Quetiapine Fumarate
C129687	Clomipramine Hydrochloride	S129789	Sertraline Hydrochloride
D276264	Desvenlafaxine succinate monohydrate	T166901	Thioridazine Hydrochloride
D131718	Doxepin Hydrochloride	T129695	Trazodone HCl
D123291	Duloxetine Hydrochloride	T162449	Trifluoperazine Hydrochloride
E122736	Escitalopram Oxalate	V129637	Venlafaxine Hydrochloride
F276205	Fluphenazine hydrochloride	V124992	Vilazodone
F129671	Fluvoxamine Maleate	V125545	Vortioxetine
I125279	Iloperidone	Z125730	Ziprasidone

Aladdin: https://www.aladdinsci.com/