GM-CSF, IL-3, and IL-5 integrate hematopoietic and immune signals through the shared βc chain, respectively regulating myeloid cells, basophils, and eosinophils, and participating in hematologic malignancies, allergy, and autoimmune inflammation.
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GM-CSF
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
5 resources · protocols, FAQs & articles
Induced pluripotent stem cells (iPSCs) have self-renewal and multilineage differentiation capacities and can be used in disease modeling, drug screening, organoid construction, and cell therapy research. Directed differentiation of iPSCs depends on stage-specific signal regulation. Activin A, ...
Within the soluble cytokine network, colony-stimulating factors (CSFs) are a group of protein factors whose defining feature is the ability to drive proliferation and differentiation of hematopoietic progenitors and to regulate the production and functional maturation of myeloid cells.
The isolation and culture of BMDC (bone marrow-derived dendritic cells) is an important technique in immunology research. This protocol will introduce how to isolate immature bone marrow-derived dendritic cells from mice.
Which cytokines show cross-species activity?
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Techniques often explored alongside immunological experiments.