10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 30 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Hesperidin (Cirantin) is a flavanone glycoside found abundantly in citrus fruits.
In vitro
In vivo
Cell Data
cell lines：hFOB cells
Concentrations：
Incubation Time：
Powder Purity:≥95%
| Isomeric SMILES | C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O |
|---|---|
| WGK Germany | 3 |
| Molecular Weight | 610.56 |
| Beilstein | 75140 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Melt Point(°C) | 250-255°C |
|---|
| 1. Min-Rui Tai, Hong-Wu Ji, Jian-Ping Chen, Xiao-Fei Liu, Bing-Bing Song, Sai-Yi Zhong, Aaqil Rifai, David R. Nisbet, Colin J. Barrow, Richard J. Williams, Rui Li. (2023) Biomimetic triumvirate nanogel complexes via peptide-polysaccharide-polyphenol self-assembly. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:37562478] [10.1016/j.ijbiomac.2023.126232] |
| 2. Hong-Qi Xia, Wanbing Chen, Diyang Qiu, Jiwu Zeng. (2023) Portable Microelectrochemical Sensors for Rapid and Sensitive Determination of Hesperidin in Citrus reticulate ‘Chachi’ Peel. MOLECULES, 28 (14): (5316). [PMID:37513189] [10.3390/molecules28145316] |
| 3. Xiao-Hua Zhang, Xiang-Dong Qing, Jing-Jing Zheng, Yan Yu, Jiaojiao Huang, Chao Kang, Zhi Liu. (2023) Aqueous two-phase systems coupled with chemometrics-enhanced HPLC-DAD for simultaneous extraction and determination of flavonoids in honey. Food Chemistry-X, [PMID:37780266] [10.1016/j.fochx.2023.100766] |
| 4. Shengxiang Yi, Gaowei Zhang, Mingyan Liu, Wenjie Yu, Guohua Cheng, Liping Luo, Fangjian Ning. (2023) Citrus Honey Ameliorates Liver Disease and Restores Gut Microbiota in Alcohol–Feeding Mice. Nutrients, 15 (5): (1078). [PMID:36904078] [10.3390/nu15051078] |
| 5. Pan Lixia, Ye Hangyu, Pi Xionge, Liu Wei, Wang Zhao, Zhang Yinjun, Zheng Jianyong. (2023) Effects of several flavonoids on human gut microbiota and its metabolism by in vitro simulated fermentation. Frontiers in Microbiology, [PMID:36819019] [10.3389/fmicb.2023.1092729] |
| 6. Hong-qi Xia, Diyang Qiu, Wanbing Chen, Genlin Mao, Jiwu Zeng. (2023) In situ formed and fully integrated laser-induced graphene electrochemical chips for rapid and simultaneous determination of bioflavonoids in citrus fruits. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2023.108474] |
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| 10. Dan Yu, Fei Liu, Changdong Zou, Xiao Yang. (2022) Municipal green waste promotes iron release from steelmaking slag in water. RESOURCES CONSERVATION AND RECYCLING, [PMID:] [10.1016/j.resconrec.2022.106722] |
| 11. Ye Hangyu, Li Xiaojun, Li Luyuan, Zhang Yinjun, Zheng Jianyong. (2022) Homologous Expression and Characterization of α-L-rhamnosidase from Aspergillus niger for the Transformation of Flavonoids. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 194 (8): (3453-3467). [PMID:35366188] [10.1007/s12010-022-03894-9] |
| 12. Hong-qi Xia, Tingting Gu, Ruiyi Fan, Jiwu Zeng. (2022) Comparative investigation of bioflavonoid electrocatalysis in 1D, 2D, and 3D carbon nanomaterials for simultaneous detection of naringin and hesperidin in fruits. RSC Advances, 12 (11): (6409-6415). [PMID:35424592] [10.1039/D1RA07217J] |
| 13. Xiangrong Li, Ruonan Xu, Zeqing Cheng, Zhizhi Song, Ziyang Wang, Hanxiao Duan, Xinzhe Wu, Tianjun Ni. (2021) Comparative study on the interaction between flavonoids with different core structures and hyaluronidase. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:34175762] [10.1016/j.saa.2021.120079] |
| 14. Dan-Hua He, Yu-Fei Chen, Yi-Le Zhou, Shi-Bing Zhang, Ming Hong, Xianjun Yu, Su-Fen Wei, Xiang-Zhen Fan, Si-Yi Li, Qi Wang, Yongzhi Lu, Yong-Qiang Liu. (2021) Phytochemical library screening reveals betulinic acid as a novel Skp2-SCF E3 ligase inhibitor in non–small cell lung cancer. CANCER SCIENCE, 112 (8): (3218-3232). [PMID:34080260] [10.1111/cas.15005] |
| 15. Lingrong Wen, Mingyang He, Chunxiao Yin, Yueming Jiang, Donghui Luo, Bao Yang. (2021) Phenolics in Citrus aurantium fruit identified by UHPLC-MS/MS and their bioactivities. LWT-FOOD SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.lwt.2021.111671] |
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| 17. Hui Guo, Yunfei Chen, Na Song, Xinyi Yang, Shen Yao, Junqing Qian. (2019) Screening of lipase inhibitors from bamboo leaves based on the magnetic ligand fishing combined with HPLC/MS. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2019.104497] |
| 18. Xinlin Chen, Shang Xue, Yaolan Lin, Jianguang Luo, Lingyi Kong. (2019) Immobilization of porcine pancreatic lipase onto a metal-organic framework, PPL@MOF: A new platform for efficient ligand discovery from natural herbs. ANALYTICA CHIMICA ACTA, [PMID:31986282] [10.1016/j.aca.2019.11.042] |
| 19. Chengyun He, Xiaoling Liu, Zhaojing Jiang, Sheng Geng, Hanjun Ma, Benguo Liu. (2019) Interaction Mechanism of Flavonoids and α-Glucosidase: Experimental and Molecular Modelling Studies. Foods, 8 (9): (355). [PMID:31438605] [10.3390/foods8090355] |
| 20. Sisi Ke, Ningrui Wang, Xingyu Chen, Jiangwei Tian, Jiwei Li, Boyang Yu. (2025) A Label-Free Colorimetric Aptasensor for Flavokavain B Detection. SENSORS, 25 (2): (569). [PMID:39860936] [10.3390/s25020569] |
| 21. Yuhan Liu, Yu Lei, Luorui Shang, Zhaomin Yu, Li Wang, Jiabin Zhou, Guangtao Pan. (2025) Protective effects of Dachengqi Decoction in sepsis-associated liver injury based on network pharmacology analysis and experimental validation. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:40840728] [10.1016/j.jep.2025.120450] |
| 22. Qi Quan, Wei Liu, Jiajing Guo, Meiling Ye, Juhua Zhang. (2022) Effect of Six Lactic Acid Bacteria Strains on Physicochemical Characteristics, Antioxidant Activities and Sensory Properties of Fermented Orange Juices. Foods, 11 (13): (1920). [PMID:35804736] [10.3390/foods11131920] |
| 23. Yating Lu, Dong Li, Li Li, Tarun Belwal, Yanqun Xu, Xingyu Lin, Zhenhua Duan, Zisheng Luo. (2020) Effects of elevated CO2 on pigment metabolism of postharvest mandarin fruit for degreening. FOOD CHEMISTRY, [PMID:32126463] [10.1016/j.foodchem.2020.126462] |
| 24. Xuexue Feng, Tielei Wu, Bingqing Yu, Yan Wang, Shian Zhong. (2017) Hydrophilic surface molecularly imprinted naringin prepared via reverse atom transfer radical polymerization with excellent recognition ability in a pure aqueous phase. RSC Advances, 7 (45): (28082-28091). [PMID:] [10.1039/C7RA00202E] |
| 25. Songbai Liu, Yuanqing Fu, Si Nian. (2014) Buffering colour fluctuation of purple sweet potato anthocyanins to acidity variation by surfactants. FOOD CHEMISTRY, [PMID:24874351] [10.1016/j.foodchem.2014.04.029] |
| 26. Xia Liu, Weiwei Ju, Erjiao Qiang, Dongning Li, Qing Liang, Meina Guo, Weijing Yun, Zhenzhen Chen. (2025) Hesperidin improves cardiac fibrosis induced by β-adrenergic activation through modulation of gut microbiota. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, [PMID:40378637] [10.1016/j.jpet.2025.103578] |
| 27. Kuan Gao, Qin Geng, Changbao Hu, Wenhui Zhang, Xin Li, Ping Tong, Anshu Yang, Zhihua Wu, Hongbing Chen. (2025) Impact of the Polyphenol Structure on the Allergenic Potential of the Peanut Allergen Ara h 2. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:40586437] [10.1021/acs.jafc.5c05337] |
| 28. Mengru Li, Wei Zhang, Yuan Huang, Xiaoying Zhang, Wuernisha Kadeer, Leihong Mao, Yuqian Jiang, Rong Tsao, Yao Tang. (2025) Unravelling the migration of bioactive and volatile compounds coupled with water sublimation from grapes to recovered water during dynamic freeze-drying. FOOD CHEMISTRY, [PMID:41075660] [10.1016/j.foodchem.2025.146536] |
| 29. Bin-Chun Li, Weijuan Dong, Bingbing Wu, Yanlong Liu, Na Han, Guo-Bin Ding. (2025) Characterization of a Thermophilic and Acidophilic GH78 α-L-Rhamnosidase from Thermotoga sp. 2812B Capable of Efficiently Hydrolyzing a Variety of Natural Flavonoid Diglycosides. Biomolecules, 16 (1): (68). [PMID:41594608] [10.3390/biom16010068] |
| 30. Wei Liu, Yanhua Sun, Zhiyong Zhu, Zi Li, Hongfang Li, Qiongyao Zeng. (2026) Sensitive Detection of Hesperidin in Citrus Peel Using Nitrogen doped Mesoporous Carbon/Metal-Organic Framework Composite-Modified Electrodes. Analytical Methods, [PMID:] [10.1039/D6AY00309E] |
