Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 17 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Lidocaine (Alphacaine) is an amide local anesthetic with anti-inflammatory properties in vitro and in vivo. It has this functions perhaps due to an attenuation of intracellular adhesion molecule-1 (ICAM-1), pro-inflammatory cytokines, and reduction of neutrophils influx.
| ALogP | 2.3 |
|---|
| Pubchem Sid | 504750696 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504750696 |
| Canonical Smiles | CCN(CC)CC(=O)NC1=C(C=CC=C1C)C |
| IUPAC Name | 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide |
| InChIKey | NNJVILVZKWQKPM-UHFFFAOYSA-N |
| INCHI | 1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17) |
| Isomeric SMILES | CCN(CC)CC(=O)NC1=C(C=CC=C1C)C |
| WGK Germany | 3 |
| RTECS | AN7525000 |
| Molecular Weight | 234.34 |
| Beilstein | 12(4)2538 |
| Reaxy-Rn | 2215784 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2215784&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Xylenes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | m-Xylenes |
| Alternative Parents | Trialkylamines Propargyl-type 1,3-dipolar organic compounds Carboximidic acids Organopnictogen compounds Organooxygen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | M-xylene - Tertiary aliphatic amine - Tertiary amine - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidic acid derivative - Carboximidic acid - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Amine - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as m-xylenes. These are aromatic compounds that contain a m-xylene moiety, which is a monocyclic benzene carrying exactly two methyl groups at the 1- and 3-positions. |
| External Descriptors | tertiary amino compound - monocarboxylic acid amide - benzenes |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 13, 2026 | L129221 | |
| Certificate of Analysis | Nov 20, 2025 | L129221 | |
| Certificate of Analysis | Nov 20, 2025 | L129221 | |
| Certificate of Analysis | Nov 20, 2025 | L129221 | |
| Certificate of Analysis | Nov 20, 2025 | L129221 | |
| Certificate of Analysis | Jul 10, 2025 | L129221 | |
| Certificate of Analysis | Jul 10, 2025 | L129221 | |
| Certificate of Analysis | Jul 10, 2025 | L129221 | |
| Certificate of Analysis | Jul 10, 2025 | L129221 | |
| Certificate of Analysis | Dec 16, 2024 | L129221 | |
| Certificate of Analysis | Dec 16, 2024 | L129221 | |
| Certificate of Analysis | Dec 16, 2024 | L129221 | |
| Certificate of Analysis | Dec 13, 2024 | L129221 | |
| Certificate of Analysis | Dec 13, 2024 | L129221 | |
| Certificate of Analysis | Dec 13, 2024 | L129221 | |
| Certificate of Analysis | Dec 13, 2024 | L129221 | |
| Certificate of Analysis | Aug 20, 2024 | L129221 | |
| Certificate of Analysis | Aug 20, 2024 | L129221 | |
| Certificate of Analysis | Aug 20, 2024 | L129221 | |
| Certificate of Analysis | Aug 20, 2024 | L129221 | |
| Certificate of Analysis | May 20, 2024 | L129221 | |
| Certificate of Analysis | May 20, 2024 | L129221 | |
| Certificate of Analysis | Apr 10, 2024 | L129221 | |
| Certificate of Analysis | Apr 10, 2024 | L129221 | |
| Certificate of Analysis | Apr 10, 2024 | L129221 | |
| Certificate of Analysis | Mar 21, 2024 | L129221 | |
| Certificate of Analysis | Mar 21, 2024 | L129221 | |
| Certificate of Analysis | Mar 21, 2024 | L129221 | |
| Certificate of Analysis | Jul 18, 2023 | L129221 | |
| Certificate of Analysis | Jul 18, 2023 | L129221 | |
| Certificate of Analysis | Jul 18, 2023 | L129221 | |
| Certificate of Analysis | Jul 07, 2023 | L129221 | |
| Certificate of Analysis | Jul 07, 2023 | L129221 | |
| Certificate of Analysis | Jul 07, 2023 | L129221 | |
| Certificate of Analysis | Sep 21, 2022 | L129221 | |
| Certificate of Analysis | Jul 11, 2022 | L129221 | |
| Certificate of Analysis | Jun 16, 2022 | L129221 | |
| Certificate of Analysis | Jun 16, 2022 | L129221 | |
| Certificate of Analysis | May 11, 2022 | L129221 |
| Solubility | Soluble in ethanol (50 mg/ml), water (9 mg/ml at 25 °C), methanol, DMSO (47 mg/ml at 25 °C), and chloroform.Soluble in chloroform, benzene, alcohol, and ether |
|---|---|
| Sensitivity | air & light sensitive |
| Boil Point(°C) | 182 °C/4 mmHg |
| Melt Point(°C) | 69 °C |
| Molecular Weight | 234.340 g/mol |
| XLogP3 | 2.300 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 5 |
| Exact Mass | 234.173 Da |
| Monoisotopic Mass | 234.173 Da |
| Topological Polar Surface Area | 32.299 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 228.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Jiezhou Pan, Haotian Liao, Guidong Gong, Yunxiang He, Qin Wang, Lang Qin, Yaoyao Zhang, Hirotaka Ejima, Blaise L. Tardy, Joseph J. Richardson, Jiaojiao Shang, Orlando J. Rojas, Yong Zeng, Junling Guo. (2023) Supramolecular nanoarchitectonics of phenolic-based nanofiller for controlled diffusion of versatile drugs in hydrogels. JOURNAL OF CONTROLLED RELEASE, [PMID:37422124] [10.1016/j.jconrel.2023.07.003] |
| 2. Meichao Liao, Lin Yang, Xiaoyue Yang, Erxu Wang, Bin Lu, Jiye Wang, Li Duan. (2022) Vortex-assisted liquid–liquid microextraction based on hydrophobic deep eutectic solvent for the urinary excretion study of Taraxacum mongolicum extract in rats. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2022.108167] |
| 3. Xiangtian Ling, Xinqi Ma, Xielan Kuang, Yuxiu Zou, Han Zhang, Han Tang, Han Du, Binbin Zhu, Hao Huang, Qing Xia, Minghao Chen, Danyi Mao, Dongli Chen, Huangxuan Shen, Jianhua Yan. (2022) Lidocaine Inhibits Myoblast Cell Migration and Myogenic Differentiation Through Activation of the Notch Pathway. Drug Design Development and Therapy, [PMID:33688167] [10.2147/DDDT.S290002] |
| 4. Ronghao Liu, Jinjie Hao, Yangyang Wang, Yuanyuan Meng, Yanzhao Yang. (2022) A separation strategy of Au(III), Pd(II) and Pt(IV) based on hydrophobic deep eutectic solvent from hydrochloric acid media. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2022.120200] |
| 5. Meichao Liao, Yang Zhao, Xiaoyue Yang, Lin Yang, E-Hu Liu, Bin Lu, Jiye Wang, Xiaopeng Liu, Yanzhong Chang, Li Duan. (2022) A greener and sustainable route for medicinal plant analysis: Recycle utilization of hydrophobic deep eutectic solvent. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2022.107372] |
| 6. Yuemei Cen, Haihang Wang, Ping Wen, Genying Xu, Feng Tian, Fenggang Bian, Xiangqiong Zeng. (2022) The development of an artificial skin membrane mimicking the lipid bilayer structure for in vitro permeation study. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, [PMID:] [10.1016/j.colsurfa.2022.128609] |
| 7. Boyou Zhang, Fei Sun, Yi Lu, Zhihao Wang, Zhiming Shen, Lei Yuan, Qiang Wu, Cong Wu, Hongcan Shi. (2022) A novel decellularized trachea preparation method for the rapid construction of a functional tissue engineered trachea to repair tracheal defects. Journal of Materials Chemistry B, 10 (25): (4810-4822). [PMID:35237780] [10.1039/D1TB02100A] |
| 8. Renchuan Liang, Jinghang Jiang, Yanyan Zheng, Ajabkhan Sailjoi, Jie Chen, Jiyang Liu, Hongxue Li. (2021) Vertically oriented mesoporous silica film modified fluorine-doped tin oxide electrode for enhanced electrochemiluminescence detection of lidocaine in serum. RSC Advances, 11 (55): (34669-34675). [PMID:35494748] [10.1039/D1RA06375H] |
| 9. Jing Li, Yanjun Jiao, Qin Luo, Weixin Hu, Shenwen Fang, Chunling Tang, Qiang Liu. (2021) Treatment of oil-based drill cuttings by hydrophobic deep eutectic solvents. CANADIAN JOURNAL OF CHEMICAL ENGINEERING, 100 (8): (1747-1754). [PMID:] [10.1002/cjce.24263] |
| 10. Jing Lu, Wenjie Tian, Linxian Cui, Bing Cai, Tingting Zhang, Nan Huang, Lei Lu, Tao Zhu. (2021) Lidocaine-eluting endotracheal tube effectively attenuates intubation related airway response. Annals of Translational Medicine, [PMID:34164505] [10.21037/atm-21-1930] |
| 11. Yongqiang Zhang, Yingying Cao, Xiangzhan Meng, Chunshan Li, Hui Wang, Suojiang Zhang. (2020) Enhancement of transdermal delivery of artemisinin using microemulsion vehicle based on ionic liquid and lidocaine ibuprofen. COLLOIDS AND SURFACES B-BIOINTERFACES, [PMID:32109824] [10.1016/j.colsurfb.2020.110886] |
| 12. Xue Ren, Man He, Beibei Chen, Bin Hu. (2019) Magnetic porous organic polymers for extraction of cardiovascular drugs in human urine samples followed by HPLC-UV. Analytical Methods, 12 (2): (141-148). [PMID:] [10.1039/C9AY02041A] |
| 13. Wenying Fan, Man He, Linna You, Xuewei Zhu, Beibei Chen, Bin Hu. (2016) Water-compatible graphene oxide/molecularly imprinted polymer coated stir bar sorptive extraction of propranolol from urine samples followed by high performance liquid chromatography-ultraviolet detection. JOURNAL OF CHROMATOGRAPHY A, [PMID:26993782] [10.1016/j.chroma.2016.03.017] |
| 14. Xuewen Cai, Lu Zheng, Erdeng Du, Rui Ma, Jun Chen, Yao Wu, Jiayao Li, Xichen Wang, Mingguo Peng. (2025) Multispectral Analysis and Molecular Simulation of the Interactions Between Perfluorodecanoic Acid/Perfluorosebacic Acid and Human Serum Albumin. JOURNAL OF MOLECULAR RECOGNITION, 38 (4): (e70008). [PMID:40602794] [10.1002/jmr.70008] |
| 15. Li Jianlong, Zhang Jinmi, Hu Maoyuan, Jin Yao, Li Sheng, Xiong Xiaoli. (2025) Construction of an enhanced electrochemical sensor for quercetin in food samples via binary MOF on MOF hybrids. MICROCHIMICA ACTA, 192 (12): (855). [PMID:41291129] [10.1007/s00604-025-07697-7] |
| 16. Yicong Jia, Hong Chen, Qianhui Zou, Sijing Chen, Jiahao Li, Yiming Chen, Liming Lu, Feng Hong, Shuhui Jia, Xiaoyuan Jing, Jiayan Ren, Fahim Muhammad, JiaYu Mi, Jing Duan, Jianxiang Liao, Qing Liu, Fuqiang Xu, Paul J. Kenny, Ming-Hu Han, Liping Wang, Zuxin Chen, Dezhi Cao, Xin-an Liu. (2026) Gut-brain cholinergic signaling mediates the antiseizure effects of Bacteroides fragilis. NEURON, [PMID:41547348] [10.1016/j.neuron.2025.11.029] |
| 17. Shutao Ma, Li Weng, Xiang Yin, Mohamed EL-Newehy, Meera Moydeen Abdulhameed, Jiahui Song, Lu Han, Linpeng Fan, Mingyi Shang, Xiumei Mo. (2026) Preparation of nanofibrous membrane-covered saccule gastric tubes and their treatment of radiation esophagitis. Acta Biomaterialia, [PMID:41839339] [10.1016/j.actbio.2026.03.019] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →