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  1. CGP 57380, Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2
    CAS: 522629-08-9 Numero EC: 637-056-6 Formula: C11H9FN6 Peso molecolare: 244.23
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: C274776
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    3-N-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
    SMILES
    C1=CC(=CC=C1NC2=C3C(=NC=NC3=NN2)N)F
    InChIKey
    UQPMANVRZYYQMD-UHFFFAOYSA-N
    InChI
    1S/C11H9FN6/c12-6-1-3-7(4-2-6)16-11-8-9(13)14-5-15-10(8)17-18-11/h1-5H,(H4,13,14,15,16,17,18)
    Sinonimi
    NSC 741567 | SR-02000000869 | A902707 | BISBENTIAMINE [MI] | NCIOpen2_009023 | SCHEMBL16714452 | NCGC00162380-01 | HM...
  2. CGP 57380, Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2
    CAS: 522629-08-9 Numero EC: 637-056-6 Formula: C11H9FN6 Peso molecolare: 244.23
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: C424479
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    3-N-(4-fluorophenyl)-2H-pyrazolo[3,4-d]pyrimidine-3,4-diamine
    SMILES
    C1=CC(=CC=C1NC2=C3C(=NC=NC3=NN2)N)F
    InChIKey
    UQPMANVRZYYQMD-UHFFFAOYSA-N
    InChI
    1S/C11H9FN6/c12-6-1-3-7(4-2-6)16-11-8-9(13)14-5-15-10(8)17-18-11/h1-5H,(H4,13,14,15,16,17,18)
    Sinonimi
    CGP 57380|522629-08-9|CGP-57380|MNK1 Inhibitor|N3-(4-fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,4-diamine|3-N-(4-fl...
  3. Cercosporamide
    CAS: 131436-22-1 Numero EC: 803-029-4 Formula: C16H13NO7 Peso molecolare: 331.28
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: C287456
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    (9aS)-8-acetyl-1,3,7-trihydroxy-9a-methyl-9-oxodibenzofuran-4-carboxamide
    SMILES
    CC(=O)C1=C(C=C2C(C1=O)(C3=C(C=C(C(=C3O2)C(=O)N)O)O)C)O
    InChIKey
    GEWLYFZWVLXQME-MRXNPFEDSA-N
    InChI
    1S/C16H13NO7/c1-5(18)10-7(20)4-9-16(2,14(10)22)12-8(21)3-6(19)11(15(17)23)13(12)24-9/h3-4,19-21H,1-2H3,(H2,17,23)/t16-/m1/s1
    Sinonimi
    (R)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9abeta-methyl-9-oxodibenzofuran-4-carboxamide | SCHEMBL12658718 | 4-Dibenz...
  4. ETC-206 (AUM 001), Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2
    CAS: 1464151-33-4 Formula: C25H20N4O2 Peso molecolare: 408.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: E413572
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    4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]benzonitrile
    SMILES
    C1COCCN1C(=O)C2=CC=C(C=C2)C3=CN4C(=NC=C4C5=CC=C(C=C5)C#N)C=C3
    InChIKey
    FWRFPHJSGLYXTD-UHFFFAOYSA-N
    InChI
    1S/C25H20N4O2/c26-15-18-1-3-20(4-2-18)23-16-27-24-10-9-22(17-29(23)24)19-5-7-21(8-6-19)25(30)28-11-13-31-14-12-28/h1-10,16-17H,11-14H2
    Sinonimi
    HY-112424 | F88611 | AUM001 | AUM-001 | s6658 | MND3WX2R7I | MS-27017 | 4-{6-[4-(morpholine-4-carbonyl)phenyl]imidazo...
  5. ETC-206 (AUM 001), Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2
    CAS: 1464151-33-4 Formula: C25H20N4O2 Peso molecolare: 408.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: E421695
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    4-[6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2-a]pyridin-3-yl]benzonitrile
    SMILES
    C1COCCN1C(=O)C2=CC=C(C=C2)C3=CN4C(=NC=C4C5=CC=C(C=C5)C#N)C=C3
    InChIKey
    FWRFPHJSGLYXTD-UHFFFAOYSA-N
    InChI
    1S/C25H20N4O2/c26-15-18-1-3-20(4-2-18)23-16-27-24-10-9-22(17-29(23)24)19-5-7-21(8-6-19)25(30)28-11-13-31-14-12-28/h1-10,16-17H,11-14H2
    Sinonimi
    HY-112424 | F88611 | AUM001 | AUM-001 | s6658 | MND3WX2R7I | MS-27017 | 4-{6-[4-(morpholine-4-carbonyl)phenyl]imidazo...
  6. SEL201
    CAS: 2095704-43-9 PubChem CID: 129052025 Formula: C19H15ClN4O Peso molecolare: 350.8
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: S413668
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    5-(3-amino-1H-indazol-6-yl)-1-[(3-chlorophenyl)methyl]pyridin-2-one
    SMILES
    C1=CC(=CC(=C1)Cl)CN2C=C(C=CC2=O)C3=CC4=C(C=C3)C(=NN4)N
    InChIKey
    YQVUADHJKWJHAF-UHFFFAOYSA-N
    InChI
    1S/C19H15ClN4O/c20-15-3-1-2-12(8-15)10-24-11-14(5-7-18(24)25)13-4-6-16-17(9-13)22-23-19(16)21/h1-9,11H,10H2,(H3,21,22,23)
    Sinonimi
    SLV-2436 | SEL201-882(1H)​-​Pyridinone,5-​(3-​amino-​1H-​indazol-​6-​yl)​-​1-​[(3-​chlorophenyl)​methyl]​-
  7. SEL201
    CAS: 2095704-43-9 PubChem CID: 129052025 Formula: C19H15ClN4O Peso molecolare: 350.8
    10mM in DMSO
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: S422541
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    5-(3-amino-1H-indazol-6-yl)-1-[(3-chlorophenyl)methyl]pyridin-2-one
    SMILES
    C1=CC(=CC(=C1)Cl)CN2C=C(C=CC2=O)C3=CC4=C(C=C3)C(=NN4)N
    InChIKey
    YQVUADHJKWJHAF-UHFFFAOYSA-N
    InChI
    1S/C19H15ClN4O/c20-15-3-1-2-12(8-15)10-24-11-14(5-7-18(24)25)13-4-6-16-17(9-13)22-23-19(16)21/h1-9,11H,10H2,(H3,21,22,23)
    Sinonimi
    SLV-2436 | SEL201-882(1H)​-​Pyridinone,5-​(3-​amino-​1H-​indazol-​6-​yl)​-​1-​[(3-​chlorophenyl)​methyl]​-
  8. Tomivosertib (eFT-508), Inhibitor of CDC like kinase 4;Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2;Inhibitor of serine/threonine kinase 17a
    CAS: 1849590-01-7 PubChem CID: 118598754 Formula: C17H20N6O2 Peso molecolare: 340.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: T413958
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    6-[(6-aminopyrimidin-4-yl)amino]-8-methylspiro[2H-imidazo[1,5-a]pyridine-3,1'-cyclohexane]-1,5-dione
    SMILES
    CC1=C2C(=O)NC3(N2C(=O)C(=C1)NC4=NC=NC(=C4)N)CCCCC3
    InChIKey
    HKTBYUWLRDZAJK-UHFFFAOYSA-N
    InChI
    1S/C17H20N6O2/c1-10-7-11(21-13-8-12(18)19-9-20-13)16(25)23-14(10)15(24)22-17(23)5-3-2-4-6-17/h7-9H,2-6H2,1H3,(H,22,24)(H3,18,19,20,21)
    Sinonimi
    (R)-Pulegone - 90% | 1849590-01-7 | UNII-U2H19X4WBV | 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2'H-spiro[cyclohexa...
  9. Tomivosertib (eFT-508), Inhibitor of CDC like kinase 4;Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2;Inhibitor of serine/threonine kinase 17a
    CAS: 1849590-01-7 PubChem CID: 118598754 Formula: C17H20N6O2 Peso molecolare: 340.38
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: T422265
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    6-[(6-aminopyrimidin-4-yl)amino]-8-methylspiro[2H-imidazo[1,5-a]pyridine-3,1'-cyclohexane]-1,5-dione
    SMILES
    CC1=C2C(=O)NC3(N2C(=O)C(=C1)NC4=NC=NC(=C4)N)CCCCC3
    InChIKey
    HKTBYUWLRDZAJK-UHFFFAOYSA-N
    InChI
    1S/C17H20N6O2/c1-10-7-11(21-13-8-12(18)19-9-20-13)16(25)23-14(10)15(24)22-17(23)5-3-2-4-6-17/h7-9H,2-6H2,1H3,(H,22,24)(H3,18,19,20,21)
    Sinonimi
    (R)-Pulegone - 90% | 1849590-01-7 | UNII-U2H19X4WBV | 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2'H-spiro[cyclohexa...
  10. HG-10-102-01, Inhibitor of Janus kinase 2;Inhibitor of leucine rich repeat kinase 2
    CAS: 1351758-81-0 Formula: C17H20ClN5O3 Peso molecolare: 377.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: C358747
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    [4-[[5-chloro-4-(methylamino)pyrimidin-2-yl]amino]-3-methoxyphenyl]-morpholin-4-ylmethanone
    SMILES
    CNC1=NC(=NC=C1Cl)NC2=C(C=C(C=C2)C(=O)N3CCOCC3)OC
    InChIKey
    YEVOZZZLKJKCCD-UHFFFAOYSA-N
    InChI
    1S/C17H20ClN5O3/c1-19-15-12(18)10-20-17(22-15)21-13-4-3-11(9-14(13)25-2)16(24)23-5-7-26-8-6-23/h3-4,9-10H,5-8H2,1-2H3,(H2,19,20,21,22)
    Sinonimi
    [4-[[5-Chloro-4-(methylamino)-2-pyrimidinyl]amino]-3-methoxyphenyl]-4-morpholinylmethanone | (E)-(4-((5-chloro-6-(met...
  11. HG-10-102-01
    CAS: 1351758-81-0 Formula: C17H20ClN5O3 Peso molecolare: 377.83
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    ◐ .Su ordinazione · 8–12 settimane Oggetto #: H1496348
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Domande frequenti

Which compounds are listed for MNK?
Compounds associated with MNK are grouped here under the MAPK/ERK Pathway classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does MNK sit within MAPK/ERK Pathway?
MNK is one target listing within the MAPK/ERK Pathway classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from MNK?
For compounds listed under MNK, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for MNK?
Browse the parent MAPK/ERK Pathway listing to reach targets neighbouring MNK, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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