Via MAPK/ERK - Gara Supplier | High Purity

Prodotti

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EHT 1864
CAS: 754240-09-0 PubChem CID: 9938202 Formula: C₂₅H₂₇F₃N₂O₄S•2HCl Peso molecolare: 581.47

≥98%(HPLC)

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: E286802
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2-(morpholin-4-ylmethyl)-5-[5-[7-(trifluoromethyl)quinolin-4-yl]sulfanylpentoxy]pyran-4-one;dihydrochloride

SMILES

C1COCCN1CC2=CC(=O)C(=CO2)OCCCCCSC3=C4C=CC(=CC4=NC=C3)C(F)(F)F.Cl.Cl

InChIKey

LSECOAJFCKFQJG-UHFFFAOYSA-N

InChI

1S/C25H27F3N2O4S.2ClH/c26-25(27,28)18-4-5-20-21(14-18)29-7-6-24(20)35-13-3-1-2-10-33-23-17-34-19(15-22(23)31)16-30-8-11-32-12-9-30;;/h4-7,14-15,17H,1-show more

Sinonimi
EHT 1864 2HCl | SW220265-1 | BCP09829 | EHT1864 | EHT-1864 | 4H-Pyran-4-one, 2-(4-morpholinylmethyl)-5-((5-((7-(trifl...
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RBC8
CAS: 361185-42-4 PubChem CID: 6626226 Formula: C₂₅H₂₀N₄O₃ Peso molecolare: 424.45

≥98%(HPLC)

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: R287516
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6-amino-4-(2,5-dimethoxyphenyl)-3-naphthalen-2-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile

SMILES

COC1=CC(=C(C=C1)OC)C2C(=C(OC3=NNC(=C23)C4=CC5=CC=CC=C5C=C4)N)C#N

InChIKey

CLMQBVUFKIKYLU-UHFFFAOYSA-N

InChI

1S/C25H20N4O3/c1-30-17-9-10-20(31-2)18(12-17)21-19(13-26)24(27)32-25-22(21)23(28-29-25)16-8-7-14-5-3-4-6-15(14)11-16/h3-12,21H,27H2,1-2H3,(H,28,29)

Sinonimi
6-Amino-4-(2,5-dimethoxyphenyl)-1,4-dihydro-3-(2-naphthalenyl)-pyrano[2,3-c]pyrazole-5-carbonitrile
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Deltarasin
CAS: 1440898-61-2 Formula: C₄₀H₃₇N₅O Peso molecolare: 603.75

≥96%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: D125721
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1-benzyl-2-[4-[(2S)-2-(2-phenylbenzimidazol-1-yl)-2-piperidin-4-ylethoxy]phenyl]benzimidazole

SMILES

C1CNCCC1C(COC2=CC=C(C=C2)C3=NC4=CC=CC=C4N3CC5=CC=CC=C5)N6C7=CC=CC=C7N=C6C8=CC=CC=C8

InChIKey

LTZKEDSUXKTTTC-KXQOOQHDSA-N

InChI

1S/C40H37N5O/c1-3-11-29(12-4-1)27-44-36-17-9-7-15-34(36)42-39(44)32-19-21-33(22-20-32)46-28-38(30-23-25-41-26-24-30)45-37-18-10-8-16-35(37)43-40(45)31show more

Sinonimi
2-[4-[(2S)-2-(2-Phenyl-1H-benzimidazol-1-yl)-2-(4-piperidinyl)ethoxy]phenyl]-1-(phenylmethyl)-1H-benzimidazole
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EHop-016
CAS: 1380432-32-5 Formula: C₂₅H₃₀N₆O Peso molecolare: 430.55

Solido Moligand™ ? ≥99%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: E129206
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4-N-(9-ethylcarbazol-3-yl)-2-N-(3-morpholin-4-ylpropyl)pyrimidine-2,4-diamine

SMILES

CCN1C2=C(C=C(C=C2)NC3=NC(=NC=C3)NCCCN4CCOCC4)C5=CC=CC=C51

InChIKey

AFTZZRFCMOAFCR-UHFFFAOYSA-N

InChI

1S/C25H30N6O/c1-2-31-22-7-4-3-6-20(22)21-18-19(8-9-23(21)31)28-24-10-12-27-25(29-24)26-11-5-13-30-14-16-32-17-15-30/h3-4,6-10,12,18H,2,5,11,13-17H2,1Hshow more

Sinonimi
N4-(9-Ethyl-9H-carbazol-3-yl)-N2-(3-morpholin-4-yl-propyl)-pyrimidine-2,4-diamine
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Salirasib, RAS inhibitor
CAS: 162520-00-5 Numero EC: 878-362-1 PubChem CID: 5469318 Formula: C₂₂H₃₀O₂S Peso molecolare: 358.54

Moligand™ ? ≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: S124985
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2-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]sulfanylbenzoic acid

SMILES

CC(=CCCC(=CCCC(=CCSC1=CC=CC=C1C(=O)O)C)C)C

InChIKey

WUILNKCFCLNXOK-CFBAGHHKSA-N

InChI

1S/C22H30O2S/c1-17(2)9-7-10-18(3)11-8-12-19(4)15-16-25-21-14-6-5-13-20(21)22(23)24/h5-6,9,11,13-15H,7-8,10,12,16H2,1-4H3,(H,23,24)/b18-11+,19-15+

Sinonimi
1-ammonionaphthalen-2-olate | 2-(3,7,11-trimethyldodeca-2,6,10-trienylsulfanyl)benzoic acid | Salirasib, >=98% (HPLC)...
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Goralatide
CAS: 120081-14-3 Formula: C₂₀H₃₃N₅O₉ Peso molecolare: 487.51

Moligand™ ? ≥90%

◐ .Su ordinazione · 8–12 settimane Oggetto #: G276013
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(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-3-carboxypropanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carboxylic acid

SMILES

CC(=O)NC(CO)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)O

InChIKey

HJDRXEQUFWLOGJ-AJNGGQMLSA-N

InChI

1S/C20H33N5O9/c1-11(27)22-14(10-26)18(31)24-13(9-16(28)29)17(30)23-12(5-2-3-7-21)19(32)25-8-4-6-15(25)20(33)34/h12-15,26H,2-10,21H2,1H3,(H,22,27)(H,23show more

Sinonimi
acetyl-N-Ser-Asp-Lys-Pro | acetyl-seryl-aspartyl-lysyl-prolinamide | CAS-120081-14-3 | GTPL10060 | acetyl-SDKP | AcSD...
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Spiclomazine
CAS: 24527-27-3 PubChem CID: 65714 Formula: C₂₂H₂₄ClN₃OS₂ Peso molecolare: 446.03

◐ .Su ordinazione · 8–12 settimane Oggetto #: S330717
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8-[3-(2-chlorophenothiazin-10-yl)propyl]-1-thia-4,8-diazaspiro[4.5]decan-3-one

SMILES

C1CN(CCC12NC(=O)CS2)CCCN3C4=CC=CC=C4SC5=C3C=C(C=C5)Cl

InChIKey

CFOYBMUYCBSDAL-UHFFFAOYSA-N

InChI

1S/C22H24ClN3OS2/c23-16-6-7-20-18(14-16)26(17-4-1-2-5-19(17)29-20)11-3-10-25-12-8-22(9-13-25)24-21(27)15-28-22/h1-2,4-7,14H,3,8-13,15H2,(H,24,27)

Sinonimi
NCI290956 | Q27278666 | Clospirazine | DTXSID9043851 | Spiclomazine [INN] | G2V8248111 | CHEBI:135727 | 8-(3-(2-Chlor...
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Kobe0065
CAS: 436133-68-5 Formula: C₁₅H₁₁ClF₃N₅O₄S Peso molecolare: 449.79

≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: K276196
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1-(3-chloro-4-methylphenyl)-3-[2,6-dinitro-4-(trifluoromethyl)anilino]thiourea

SMILES

CC1=C(C=C(C=C1)NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])Cl

InChIKey

KSJVAYBCXSURMQ-UHFFFAOYSA-N

InChI

1S/C15H11ClF3N5O4S/c1-7-2-3-9(6-10(7)16)20-14(29)22-21-13-11(23(25)26)4-8(15(17,18)19)5-12(13)24(27)28/h2-6,21H,1H3,(H2,20,22,29)

Sinonimi
AS-16550 | EX-A370 | N-(3-chloro-4-methylphenyl)-2-(2,6-dinitro-4-(trifluoromethyl)phenyl)hydrazinecarbothioamide. | ...
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Kobe2602
CAS: 454453-49-7 Formula: C₁₄H₉F₄N₅O₄S Peso molecolare: 419.31

≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: K275031
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1-[2,6-dinitro-4-(trifluoromethyl)anilino]-3-(4-fluorophenyl)thiourea

SMILES

C1=CC(=CC=C1NC(=S)NNC2=C(C=C(C=C2[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-])F

InChIKey

NNPBSITXCGPXJC-UHFFFAOYSA-N

InChI

1S/C14H9F4N5O4S/c15-8-1-3-9(4-2-8)19-13(28)21-20-12-10(22(24)25)5-7(14(16,17)18)6-11(12)23(26)27/h1-6,20H,(H2,19,21,28)

Sinonimi
2-(2,6-dinitro-4-(trifluoromethyl)phenyl)-N-(4-fluorophenyl)hydrazinecarbothioamide
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Ketoconazolo, Inhibitor of CYP3A4;Channel blocker of K v1.8
CAS: 65277-42-1 Numero EC: 265-667-4 Formula: C₂₆H₂₈Cl₂N₄O₄ Peso molecolare: 531.43

Solido Moligand™ ? ≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: K129737
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1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone

SMILES

CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl

InChIKey

XMAYWYJOQHXEEK-OZXSUGGESA-N

InChI

1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-show more

Sinonimi
HMS3678J17 | Ketoconazole (k) | KTZ | MLS002222255 | N-(1,3,4-Trihydroxyoctadecan-2-yl)octadecanimidic acid | NCGC000...
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N-Acetylneuraminic acid(Neu5Ac)
CAS: 131-48-6 Numero EC: 205-023-1 Formula: C₁₁H₁₉NO₉ Peso molecolare: 309.27

Solido Moligand™ ? ≥98%

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: A100555
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(2S,4S,5R,6R)-5-acetamido-2,4-dihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid

SMILES

CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)O)O

InChIKey

SQVRNKJHWKZAKO-PFQGKNLYSA-N

InChI

1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11-/m0/s1

Sinonimi
NAN | NANA | b-5-acetamido-3,5-dideoxy-D-glycero-D-galacto-Nonulopyranosonate | N-Acetyl-b-neuraminate | N-Acetylsial...
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NAV 2729
CAS: 419547-11-8 Formula: C₂₅H₁₇ClN₄O₃ Peso molecolare: 456.88

≥98%(HPLC)

● In magazzino — Magazzino negli USA, spedizione nell'EU* Oggetto #: N288414
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2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one

SMILES

C1=CC=C(C=C1)CC2=C(C3=NC(=CC(=O)N3N2)C4=CC=C(C=C4)[N+](=O)[O-])C5=CC=C(C=C5)Cl

InChIKey

WHYGBVWGARJOCS-UHFFFAOYSA-N

InChI

1S/C25H17ClN4O3/c26-19-10-6-18(7-11-19)24-22(14-16-4-2-1-3-5-16)28-29-23(31)15-21(27-25(24)29)17-8-12-20(13-9-17)30(32)33/h1-13,15,28H,14H2

Sinonimi
NAV-2729 | NAV2729

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Domande frequenti

How is the Ras listing put together?

It draws on reported Ras annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.

How do I choose a Ras modulator for my assay?

Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Ras entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.

Which specifications matter most for Ras compounds?

Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Ras work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

What if the Ras compound I need is not listed?

Search by CAS number or SMILES first, since analogs of Ras compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.