Cellule staminali/Wnt - TGF-beta/Smad Supplier | High Purity

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SIS 3 Hydrochloride
CAS: 521984-48-5 PubChem CID: 16079005 Formula: C₂₈H₂₇N₃O₃•HCl Peso molecolare: 489.99

≥98%

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(E)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one;hydrochloride

SMILES

CN1C(=C(C2=C1N=CC=C2)C=CC(=O)N3CCC4=CC(=C(C=C4C3)OC)OC)C5=CC=CC=C5.Cl

InChIKey
CDKIEBFIMCSCBB-CALJPSDSSA-N

InChI

1S/C28H27N3O3.ClH/c1-30-27(19-8-5-4-6-9-19)22(23-10-7-14-29-28(23)30)11-12-26(32)31-15-13-20-16-24(33-2)25(34-3)17-21(20)18-31;/h4-12,14,16-17H,13,15,show more

Sinonimi
(E)-1-[6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl]-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-...
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Pirfenidone
CAS: 53179-13-8 Numero EC: 621-260-7 Formula: C₁₂H₁₁NO Peso molecolare: 185.22

Solido Moligand™ ? ≥98%(GC)

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5-methyl-1-phenylpyridin-2-one

SMILES

CC1=CN(C(=O)C=C1)C2=CC=CC=C2

InChIKey
ISWRGOKTTBVCFA-UHFFFAOYSA-N

InChI

1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3

Sinonimi
MFCD00866047 | Pirfenidona [INN-Spanish] | PIRFENIDONE [INN] | Pirfenidone(AMR69) | 5-Methyl-1-phenyl-2(1H)-pyridone ...
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Trimethylamine N-Oxide(TMANO)
CAS: 1184-78-7 Numero EC: 214-675-6 PubChem CID: 1145 Formula: C₃H₉NO Peso molecolare: 75.11

Solido Moligand™ ? ≥95%(T)

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N,N-dimethylmethanamine oxide

SMILES

C[N+](C)(C)[O-]

InChIKey
UYPYRKYUKCHHIB-UHFFFAOYSA-N

InChI

1S/C3H9NO/c1-4(2,3)5/h1-3H3

Sinonimi
Trimethylamine oxide | NSC 408426 | MFCD00002048 | Trimethlamine-N-oxide | Triox | CHEBI:15724 | EN300-396337 | Trime...
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Neohesperidin
CAS: 13241-33-3 Numero EC: 236-216-9 Formula: C₂₈H₃₄O₁₅ Peso molecolare: 610.56

Solido Analytical standard ? Moligand™ ? ≥97%

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(2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxshow more

SMILES

CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)O)O)CO)O)O)O)O)O

InChIKey
ARGKVCXINMKCAZ-UZRWAPQLSA-N

InChI

1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/hshow more

Sinonimi
(S)-7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-...
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Trimethylamine-d9 N-Oxide
CAS: 1161070-49-0 PubChem CID: 71752814 Formula: C₃D₉NO Peso molecolare: 84.17

≥98 atom% D,≥98%

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1,1,1-trideuterio-N,N-bis(trideuteriomethyl)methanamine oxide

SMILES

C[N+](C)(C)[O-]

InChIKey
UYPYRKYUKCHHIB-GQALSZNTSA-N

InChI

1S/C3H9NO/c1-4(2,3)5/h1-3H3/i1D3,2D3,3D3

Sinonimi
Trimethylamine N-oxide-d9 | Trimethylamine-d9 N-Oxide, 98 atom % D, 98% (CP) | 1,1,1-trideuterio-N,N-bis(trideuteriom...
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Asiaticoside
CAS: 16830-15-2 Numero EC: 240-851-7 Formula: C₄₈H₇₈O₁₉ Peso molecolare: 959.12

Solido Analytical standard ? Moligand™ ? ≥98%

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[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-show more

SMILES

CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)OC6C(C(C(C(O6)COC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)O)O)O)O

InChIKey
WYQVAPGDARQUBT-FGWHUCSPSA-N

InChI

1S/C48H78O19/c1-20-10-13-48(15-14-46(6)23(29(48)21(20)2)8-9-28-44(4)16-24(51)39(60)45(5,19-50)27(44)11-12-47(28,46)7)43(61)67-42-36(58)33(55)31(53)26(show more

Sinonimi
(-)-SENECIONINE | NSC-36002 | (2alpha,3beta,4alpha)-2,3,23-TRIHYDROXYURS-12-EN-28-OIC ACID O-6-DEOXY-alpha-L-MANNOPYR...
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Ammothamnine
CAS: 16837-52-8 Numero EC: 605-514-4 Formula: C₁₅H₂₄N₂O₂ Peso molecolare: 264.36

≥98%(HPLC)

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(1R,2R,9S,17S)-13-oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one

SMILES

C1CC2C3CCC[N+]4(C3C(CCC4)CN2C(=O)C1)[O-]

InChIKey
XVPBINOPNYFXID-LHDUFFHYSA-N

InChI

1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-,17?/m0/s1

Sinonimi
Pachycarpidine | BDBM50597716 | Oxymatrine | BBL030371 | MLS001215101 | rel-(41S,7aS,13aR,13bR)-10-Oxohexadecahydrodi...
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Alantolactone
CAS: 546-43-0 Formula: C₁₅H₂₀O₂ Peso molecolare: 232.32

Analytical standard ? ≥97%(HPLC)

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(3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylidene-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one

SMILES

CC1CCCC2(C1=CC3C(C2)OC(=O)C3=C)C

InChIKey
PXOYOCNNSUAQNS-AGNJHWRGSA-N

InChI

1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1

Sinonimi
(3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylene-3,3a,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(5H)-one | Q21099633 | DT...
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Halofuginone hydrobromide
CAS: 64924-67-0 Formula: C₁₆H₁₇BrClN₃O₃•HBr Peso molecolare: 495.59

≥98%(HPLC)

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7-bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one;hydrobromide

SMILES

C1CC(C(NC1)CC(=O)CN2C=NC3=CC(=C(C=C3C2=O)Cl)Br)O.Br

InChIKey
SJUWEPZBTXEUMU-LDXVYITESA-N

InChI

1S/C16H17BrClN3O3.BrH/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14;/h5-6,8,14-15,19,23H,1-4,7H2;1H/t14-,15+;/m0./s1

Sinonimi
MFCD00017259 | RU-19110 (hydrobromide) | Halofuginone hydrobromide, (-)- | AMY26820 | HY-N1584A | AKOS015920268 | Hal...
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Kartogenin
CAS: 4727-31-5 Formula: C₂₀H₁₅NO₃ Peso molecolare: 317.34

Solido Moligand™ ? ≥98%(HPLC)

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2-[(4-phenylphenyl)carbamoyl]benzoic acid

SMILES

C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O

InChIKey
SLUINPGXGFUMLL-UHFFFAOYSA-N

InChI

1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)

Sinonimi
KGN | 2-[[1,1'-Biphenyl]-4-ylcarbamoyl]benzoic Acid | 2-[(Biphenyl-4-yl)carbamoyl]benzoic acid | 4'-Phenyl-phthalanil...
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R 268712
CAS: 879487-87-3 PubChem CID: 11703284 Formula: C₂₀H₁₈FN₅O Peso molecolare: 363.39

≥98%(HPLC)

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2-[4-[2-fluoro-5-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]phenyl]pyrazol-1-yl]ethanol

SMILES

CC1=NC(=CC=C1)C2=C(C=NN2)C3=CC(=C(C=C3)F)C4=CN(N=C4)CCO

InChIKey
JQGOCCALXFSRHZ-UHFFFAOYSA-N

InChI

1S/C20H18FN5O/c1-13-3-2-4-19(24-13)20-17(11-22-25-20)14-5-6-18(21)16(9-14)15-10-23-26(12-15)7-8-27/h2-6,9-12,27H,7-8H2,1H3,(H,22,25)

Sinonimi
SCHEMBL5198271 | C20H18FN5O | NCGC00387472-01 | 4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-py...
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Neohesperidin
CAS: 13241-33-3 Numero EC: 236-216-9 Formula: C₂₈H₃₄O₁₅ Peso molecolare: 610.56

Solido Moligand™ ? ≥97%

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(2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxshow more

SMILES

CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)O)O)CO)O)O)O)O)O

InChIKey
ARGKVCXINMKCAZ-UZRWAPQLSA-N

InChI

1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/hshow more

Sinonimi
(S)-7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-...

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Domande frequenti

How is the TGF-beta/Smad listing put together?

It draws on reported TGF-beta/Smad annotations within Stem Cell/Wnt and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.

How do I choose a TGF-beta/Smad modulator for my assay?

Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the TGF-beta/Smad entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.

Which specifications matter most for TGF-beta/Smad compounds?

Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For TGF-beta/Smad work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

What if the TGF-beta/Smad compound I need is not listed?

Search by CAS number or SMILES first, since analogs of TGF-beta/Smad compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.