Mitonafide - Moligand™, ≥98% , CAS No.54824-17-8

Name: Mitonafide - Moligand™, ≥98% , CAS No.54824-17-8
Brand: Aladdin Scientific
SKU: M334186
Availability: InStock

CAS: 54824-17-8 Cat. No.: M334186 Formula: C₁₆H₁₅N₃O₄ Peso molecolare: 313.31

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Mitonafide - Moligand™, ≥98% CAS No(54824-17-8) M334186 by Aladdin Scientific

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QUALITÀ & PUREZZA Moligand™ ? ≥98%

Synonyms

NAPHTHALIMIDE, 2-(2-(DIMETHYLAMINO)ETHYL)-5-NITRO-|1H-Benz[de]isoquinoline-1,3 (2H)-dione, 2-[2-(Dimethylamino)ethyl]-5-nitro-|2-(2-dimethylaminoethyl)-5-nitro-benzo[de]isoquinoline-1,3-dione

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Scheda delle specifiche

Panoramica Specifiche Nomi e identificatori Dati avanzati Taxonomic Classification Struttura 3D Obiettivi associati (umani) Obiettivi associati (non umani) Meccanismi d'azione Certificati (CoA, COO, BSE/TSE e tabella di analisi) Proprietà chimiche e fisiche Calcolatori di soluzioni Recensioni

Panoramica

Mitonafide (NSC 300288) is a cytostatic agent. Mitonafide binds to double-stranded DNA through intercalation, and inhibits DNA and RNA synthesis. Mitonafide is an antitumor agent that can be used in the research of cancers, such as non-small cell lung cancer (NSCLC), leukemia.

Specifiche

Sinonimi

NAPHTHALIMIDE, 2-(2-(DIMETHYLAMINO)ETHYL)-5-NITRO- | 1H-Benz[de]isoquinoline-1,3 (2H)-dione, 2-[2-(Dimethylamino)ethyl]-5-nitro- | 2-(2-dimethylaminoethyl)-5-nitro-benzo[de]isoquinoline-1,3-dione

Specifiche e purezza

Moligand™, ≥98%

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Grado

Moligand™

Tipo di azione

INHIBITOR

Purezza

≥98%

Nomi e identificatori

Pubchem Sid

528765641

Sorrisi canonici

CN(C)CCN1C(=O)C2=CC=CC3=CC(=CC(=C32)C1=O)[N+](=O)[O-]

IUPAC Name

2-[2-(dimethylamino)ethyl]-5-nitrobenzo[de]isoquinoline-1,3-dione

InChIKey

XXVLKDRPHSFIIB-UHFFFAOYSA-N

INCHI

1S/C16H15N3O4/c1-17(2)6-7-18-15(20)12-5-3-4-10-8-11(19(22)23)9-13(14(10)12)16(18)21/h3-5,8-9H,6-7H2,1-2H3

Isomeri SMILES

CN(C)CCN1C(=O)C2=CC=CC3=CC(=CC(=C32)C1=O)[N+](=O)[O-]

Peso molecolare

313.31

Reaxy-Rn

1550151

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1550151&ln=

Dati avanzati

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Classe Naphthalenes
    - Subclass Nitronaphthalenes

Kingdom	Organic compounds
Superclass	Benzenoids
Classe	Naphthalenes
Subclass	Nitronaphthalenes
Intermediate Tree Nodes	Not available
Direct Parent	Nitronaphthalenes
Alternative Parents	Isoquinolones and derivatives Nitroaromatic compounds N-substituted carboxylic acid imides Trialkylamines Amino acids and derivatives Propargyl-type 1,3-dipolar organic compounds Organic oxoazanium compounds Azacyclic compounds Organooxygen compounds Organic salts Organic oxides Hydrocarbon derivatives Organic cations
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	2-nitronaphthalene - Isoquinolone - Nitroaromatic compound - Carboxylic acid imide, n-substituted - Carboxylic acid imide - Amino acid or derivatives - C-nitro compound - Tertiary amine - Tertiary aliphatic amine - Organic nitro compound - Propargyl-type 1,3-dipolar organic compound - Allyl-type 1,3-dipolar organic compound - Azacycle - Carboxylic acid derivative - Organoheterocyclic compound - Organic 1,3-dipolar compound - Organic oxoazanium - Organic nitrogen compound - Organic salt - Organonitrogen compound - Hydrocarbon derivative - Amine - Organic oxide - Organic oxygen compound - Organooxygen compound - Organic cation - Aromatic heteropolycyclic compound
Descrizione	This compound belongs to the class of organic compounds known as nitronaphthalenes. These are polycyclic aromatic compounds containing a naphthalene moiety substituted by one or more nitro groups.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Struttura 3D

Obiettivi associati (umani)

TOP2A Tclin DNA topoisomerase II alpha (6317 Activities)

Discover Target: TOP2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

Discover Target: GLP1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)

Discover Target: PIN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A-375 (9258 Activities)

Lot Number	Certificate Type	Data	Oggetto
G2523476	Certificate of Analysis	Feb 11, 2025	M334186
G2523482	Certificate of Analysis	Feb 11, 2025	M334186
G2523483	Certificate of Analysis	Feb 11, 2025	M334186
G2523484	Certificate of Analysis	Feb 11, 2025	M334186
G2523486	Certificate of Analysis	Feb 11, 2025	M334186
G2523488	Certificate of Analysis	Feb 11, 2025	M334186

Punto di fusione (°C)	137-141° C
Peso molecolare	313.310 g/mol
XLogP3	2.000
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	3
Exact Mass	313.106 Da
Monoisotopic Mass	313.106 Da
Topological Polar Surface Area	86.400 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	516.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Mitonafide - Moligand™, ≥98% , CAS No.54824-17-8

Panoramica

Specifiche

Dati avanzati

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