Mosapride Citrate - ≥98% , CAS No.112885-42-4

CAS: 112885-42-4 Cat. No.: M129673 Formula: C₂₁H₂₅ClFN₃O₃·C₆H₈O₇ Peso molecolare: 614.02 Numero EC: 601-211-6

GRADE & PURITY ≥98%

Synonyms

AKOS015895400 | DTXCID5026207 | Mosapride citrate - Adooq Bioscience | (+/-)-4-AMINO-5-CHLORO-2-ETHOXY-N-((4-(P-FLUOROBENZYL)-2-MORPHOLINYL)METHYL)BENZAMIDE CITRATE | MOSAPRIDE CITRATE [WHO-DD] | TAK370 | TAK-370 | Mosapride citrate- Bio-X | TAK-370 citra

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Panoramica

A selective SR-4 activator and a SR-3 inhibitor.

Specifications

Sinonimi

AKOS015895400 | DTXCID5026207 | Mosapride citrate - Adooq Bioscience | (+/-)-4-AMINO-5-CHLORO-2-ETHOXY-N-((4-(P-FLUOROBENZYL)-2-MORPHOLINYL)METHYL)BENZAMIDE CITRATE | MOSAPRIDE CITRATE [WHO-DD] | TAK370 | TAK-370 | Mosapride citrate- Bio-X | TAK-370 citra

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

Mosapride citrate is a selective SR-4 agonist and SR-3 antagonist. Increases gastric emptying in rats and stimulates gastric motor activity in conscious dogs.Potent and selective 5-HT 4 agonist. Enhances electrically-evoked ileum contractions (EC 50 = 73

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purezza

≥98%

Nomi e identificatori

• Pubchem Sid: 528772159
• Sorrisi canonici: CCOC1=CC(=C(C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(C=C3)F)Cl)N.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
• IUPAC Name: 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;2-hydroxypropane-1,2,3-tricarboxylic acid
• InChIKey: HUZTYZBFZKRPFG-UHFFFAOYSA-N
• INCHI: 1S/C21H25ClFN3O3.C6H8O7/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
• Isomeri SMILES: CCOC1=CC(=C(C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(C=C3)F)Cl)N.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
• CAS alternativo: 112885-42-4
• Termini MeSH: 4-amino-5-chloro-2-ethoxy-N-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide;AS 4370;AS-4370;mosapride;mosapride citrate;Mosapride UI05MSP015CT
• Peso molecolare: 614.02
• Reaxy-Rn: 4288606
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4288606&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Tricarboxylic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Tricarboxylic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Tricarboxylic acids and derivatives
• Alternative Parents: Aminophenyl ethers Phenylmethylamines Phenoxy compounds Aniline and substituted anilines Benzylamines Alkyl aryl ethers Aralkylamines Fluorobenzenes Chlorobenzenes Alpha hydroxy acids and derivatives Aryl chlorides Aryl fluorides Morpholines Tertiary alcohols Trialkylamines Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Azacyclic compounds Carboximidic acids Carboxylic acids Dialkyl ethers Organic oxides Primary amines Hydrocarbon derivatives Carbonyl compounds Organopnictogen compounds Organofluorides Organochlorides
• Molecular Framework: Not available
• Substituents: Aminophenyl ether - Tricarboxylic acid or derivatives - Phenoxy compound - Phenol ether - Phenylmethylamine - Benzylamine - Aniline or substituted anilines - Alkyl aryl ether - Halobenzene - Fluorobenzene - Aralkylamine - Chlorobenzene - Morpholine - Oxazinane - Alpha-hydroxy acid - Monocyclic benzene moiety - Aryl halide - Benzenoid - Aryl fluoride - Hydroxy acid - Aryl chloride - Tertiary alcohol - Tertiary amine - Tertiary aliphatic amine - Oxacycle - Azacycle - Carboximidic acid - Carboximidic acid derivative - Carboxylic acid - Organoheterocyclic compound - Dialkyl ether - Ether - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organopnictogen compound - Amine - Organic oxygen compound - Carbonyl group - Organic oxide - Hydrocarbon derivative - Alcohol - Organic nitrogen compound - Primary amine - Organooxygen compound - Organohalogen compound - Organochloride - Organofluoride - Organonitrogen compound - Aromatic heteromonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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ATXN2 Tbio Ataxin-2 (54410 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

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Adra2c Adrenergic receptor alpha-2 (3313 Activities)

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Htr2b Serotonin 2 (5-HT2) receptor (2078 Activities)

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Htr1b Serotonin 1 (5-HT1) receptor (408 Activities)

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Meccanismi d'azione

Proprietà chimiche e fisiche

• Solubilità: Soluble in DMSO (100 mM), and ethanol (10 mM).
• Peso molecolare: 614.000 g/mol
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 12
• Exact Mass: 613.184 Da
• Monoisotopic Mass: 613.184 Da
• Topological Polar Surface Area: 209.000 Ų
• Heavy Atom Count: 42
• Formal Charge: 0
• Complexity: 749.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3