MS0015203 - ≥98% , CAS No.73912-52-4

CAS: 73912-52-4 Cat. No.: M288855 Formula: C₁₂H₁₁NO₅ Peso molecolare: 249.22 Numero EC: 110-853-1

GRADE & PURITY ≥98%

Synonyms

F87723 | MS0015203 | SCHEMBL11227444 | AB00075034-01 | AKOS000640215 | STK894855 | 5-metacrilammidoisoftalicacido | HY-116797 | MS-23526 | 5-[(2-metilacrilolo)ammino]benzene-1,3-dicarbossilico | 5-[(2-metil-1-osso-2-propen-1-il)ammino]-1,3-benzenedicar

Storage

Al riparo dalla luce, conservare a -20°C

Shipped In

Cassetta del ghiaccio + cuscini per il ghiaccio

Panoramica

MS15203 è un agonista GPR171 potente e selettivo. MS15203 aumenta l'assunzione di cibo e il peso corporeo. MS15203 aumenta l'attività neuronale. MS15203 aumenta significativamente l'abbondanza degli mRNA che codificano proSAAS, NPY e AgRP.

Specifications

Sinonimi

F87723 | MS0015203 | SCHEMBL11227444 | AB00075034-01 | AKOS000640215 | STK894855 | 5-metacrilammidoisoftalicacido | HY-116797 | MS-23526 | 5-[(2-metilacrilolo)ammino]benzene-1,3-dicarbossilico | 5-[(2-metil-1-osso-2-propen-1-il)ammino]-1,3-benzenedicar

Specifiche e purezza

≥98%

Meccanismi biochimici e fisiologici

Agonista parziale GPR171 potente e selettivo (EC50= 90 nM; inibizione del 28% dell'attività dell'adenilciclasi attivata dalla forskolina nelle memebrane ipotalamiche di ratto). Presenta un legame minimo con un gruppo di ~70 GPCR e 10 altri recettori (<22%

Condizioni di conservazione di stoccaggio

Al riparo dalla luce, conservare a -20°C

Spedito in

Cassetta del ghiaccio + cuscini per il ghiaccio

Purezza

≥98%

Nomi e identificatori

• Pubchem Sid: 528765567
• Sorrisi canonici: CC(=C)C(=O)NC1=CC(=CC(=C1)C(=O)O)C(=O)O
• IUPAC Name: 5-(2-methylprop-2-enoylamino)benzene-1,3-dicarboxylic acid
• InChIKey: NVOBVSWSDYFEMR-UHFFFAOYSA-N
• INCHI: 1S/C12H11NO5/c1-6(2)10(14)13-9-4-7(11(15)16)3-8(5-9)12(17)18/h3-5H,1H2,2H3,(H,13,14)(H,15,16)(H,17,18)
• Isomeri SMILES: CC(=C)C(=O)NC1=CC(=CC(=C1)C(=O)O)C(=O)O
• Peso molecolare: 249.22
• Reaxy-Rn: 5956060
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5956060&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Benzoic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Benzoic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Acylaminobenzoic acid and derivatives
• Alternative Parents: M-phthalic acid and derivatives Benzoic acids Anilides N-arylamides Benzoyl derivatives Dicarboxylic acids and derivatives Secondary carboxylic acid amides Carboxylic acids Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Acylaminobenzoic acid or derivatives - Meta_phthalic_acid - Benzoic acid - Anilide - Benzoyl - N-arylamide - Dicarboxylic acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Carboxylic acid - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Aromatic homomonocyclic compound
• Descrizione: This compound belongs to the class of organic compounds known as acylaminobenzoic acid and derivatives. These are derivatives of amino benzoic acid derivatives where the amine group is N-acylated.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Proprietà chimiche e fisiche

• Solubilità: Solvent:DMSO, Max Conc. mg/mL: 24.92, Max Conc. mM: 100
• Sensibilità: Light sensitive
• Peso molecolare: 249.220 g/mol
• XLogP3: 1.100
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 249.064 Da
• Monoisotopic Mass: 249.064 Da
• Topological Polar Surface Area: 104.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 368.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1