MU1210 , CAS No.2275601-87-9

CAS: 2275601-87-9 Cat. No.: M1425991 PubChem CID: 155891794

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Store at -20°C

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Panoramica

MU1210 (compound 12f) is an inhibitor of CDC-like kinases Clk1 , Clk2 , and Clk4 (with IC 50 values of 8, 20, and 12 nM respectively), with IC 50 for HIPK1 and DYRK2 are 187 and 1309 nM. MU1210 also has favorable pharmacokinetic characteristics (in mice, 10 mg/kg, intraperitoneal injection: C max =1.24 μM, T 1/2 =58 minutes; no acute toxicity observed).

Specifications

Condizioni di conservazione di stoccaggio

Store at -20°C

Spedito in

Ice chest + Ice pads

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Tipo di azione

INHIBITOR

Nomi e identificatori

• Sorrisi canonici: CN1C=C(C=N1)C2=NC3=C(C=C2)OC=C3C4=CC=CC(=C4)C5=CC=NC=C5
• IUPAC Name: 5-(1-methylpyrazol-4-yl)-3-(3-pyridin-4-ylphenyl)furo[3,2-b]pyridine
• InChIKey: HEAGNKNMQVIVMM-UHFFFAOYSA-N
• INCHI: 1S/C22H16N4O/c1-26-13-18(12-24-26)20-5-6-21-22(25-20)19(14-27-21)17-4-2-3-16(11-17)15-7-9-23-10-8-15/h2-14H,1H3
• Isomeri SMILES: CN1C=C(C=N1)C2=NC3=C(C=C2)OC=C3C4=CC=CC(=C4)C5=CC=NC=C5
• PubChem CID: 155891794