≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Panoramica
Rasarfin is a dual Ras and ARF6 inhibitor.
In Vitro
Rasarfin potently inhibits agonist-induced ERK1/2 signaling by GPCRs, and MAPK and Akt signaling by EGFR, as well as prevents cancer cell proliferation. ?\nRasarfin blocks GPCR internalization through inhibition of ARF6. ?\nRasarfin treatment results in a dose-dependent reduction in MDA-MB-231 cells. ?\nRasarfin inhibits the recruitment of the clathrin adaptor AP-2 to β-arrestin2 and receptor internalization, both processes that require active ARF6. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Specifications
Specifiche e purezza
≥98%
Meccanismi biochimici e fisiologici
Rasarfin is a dual Ras and ARF6 inhibitor.
Condizioni di conservazione di stoccaggio
Store at -20°C
Spedito in
Ice chest + Ice pads
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
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