(RS)-APICA , CAS No.170847-18-4

CAS: 170847-18-4 Cat. No.: R288714 Formula: C10H12NO5P Peso molecolare: 257.18 PubChem CID: 4694355
Disponibile su ordine
Synonyms
(S)-MPPG (cyclic) | AKOS024456371 | (RS)-1-Amino-5-phosphonoindan-1-carboxylic acid | 1-Amino-5-phosphono-indan-1-carboxylic acid | DTXSID201028297 | 1-Amino-5-phosphono-indan-1-carboxylic acid(RS-APICA) | HY-101375 | SR-01000597477 | 1-amino-5-phosphono-
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
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Size
Germania (EU)
USA*
Price
Qty
10mg
R288714-10mg
Su ordinazione · 8–12 settimane
301,02€
50mg
R288714-50mg
Su ordinazione · 8–12 settimane
1.232,10€
Enter a quantity for the sizes you want to add.
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Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinonimi
(S)-MPPG (cyclic) | AKOS024456371 | (RS)-1-Amino-5-phosphonoindan-1-carboxylic acid | 1-Amino-5-phosphono-indan-1-carboxylic acid | DTXSID201028297 | 1-Amino-5-phosphono-indan-1-carboxylic acid(RS-APICA) | HY-101375 | SR-01000597477 | 1-amino-5-phosphono-
Meccanismi biochimici e fisiologici
Rigidified analog of MPPG; selective group II metabotropic glutamate receptor antagonist (IC50= 30μM) with no significant effect on group I and III mGlu receptors at concentrations up to 1 mM. Increases extracellular glutamate concentrations and possesses
Condizioni di conservazione di stoccaggio
Store at 2-8°C,Desiccated
Spedito in
Wet ice
Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.
Tipo di azione
ANTAGONIST
Nomi e identificatori
Sorrisi canonici
C1CC(C2=C1C=C(C=C2)P(=O)(O)O)(C(=O)O)N
IUPAC Name
1-amino-5-phosphono-2,3-dihydroindene-1-carboxylic acid
InChIKey
ZNQZXIHSJUDIKL-UHFFFAOYSA-N
INCHI
1S/C10H12NO5P/c11-10(9(12)13)4-3-6-5-7(17(14,15)16)1-2-8(6)10/h1-2,5H,3-4,11H2,(H,12,13)(H2,14,15,16)
Isomeri SMILES
C1CC(C2=C1C=C(C=C2)P(=O)(O)O)(C(=O)O)N
PubChem CID
4694355
Peso molecolare
257.18

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClasseCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives
Direct ParentAlpha amino acids
Alternative Parents Indanes  Aralkylamines  Organic phosphonic acids  Amino acids  Monocarboxylic acids and derivatives  Carboxylic acids  Organophosphorus compounds  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic homopolycyclic compounds
Substituents Alpha-amino acid - Indane - Aralkylamine - Benzenoid - Organophosphonic acid - Organophosphonic acid derivative - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Amine - Primary aliphatic amine - Organic oxygen compound - Organic oxide - Carbonyl group - Organophosphorus compound - Primary amine - Aromatic homopolycyclic compound
DescrizioneThis compound belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).
External Descriptors Not available
Struttura 3D
Modello di struttura chimica interattiva





Obiettivi associati (umani)
GRM6 Tchem Metabotropic glutamate receptor 6 (361 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRM1 Tchem Metabotropic glutamate receptor 1 (2309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRM5 Tchem Metabotropic glutamate receptor 5 (5733 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Obiettivi associati (non umani)
Grm2 Metabotropic glutamate receptor 2 (1326 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Meccanismi d'azione
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Proprietà chimiche e fisiche
SolubilitàSolvent:1.1eq. NaOH, Max Conc. mg/mL: None, Max Conc. mM: 100
Peso molecolare257.180 g/mol
XLogP3-3.500
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass257.045 Da
Monoisotopic Mass257.045 Da
Topological Polar Surface Area121.000 Ų
Heavy Atom Count17
Formal Charge0
Complexity381.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calcolatori di soluzioni
Recensioni

Recensioni dei clienti

Domande frequenti

How should this product be stored?
Store at 2–8 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.
How is this product shipped?
This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 170847-18-4, the molecular formula is C10H12NO5P, and the molecular weight is 257.18 g/mol. InChIKey ZNQZXIHSJUDIKL-UHFFFAOYSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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