TRV056 - ≥99% , CAS No.812644-79-4

CAS: 812644-79-4 Cat. No.: T648017 Formula: C₅₂H₇₄N₁₄O₁₃ Peso molecolare: 1103.23

QUALITÀ & PUREZZA ≥99%

Storage

Protected from light,Argon charged,Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Panoramica

TRV056 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV056 is efficacious in stimulating cellular Gq-mediated signaling. TRV056 can be used to develop the Gq-biased AT1R agonists.

In Vitro

TRV056 is a “gain-of-function” ligand that have >10-fold greater allosteric coupling to Gq than AngII and is also more efficacious in stimulating cellular Gq-mediated signaling (e.g., IP1 generation). Compared to the endogenous ligand angiotensin II (AngII), “Gq-biased” AT1R agonists are more efficacious in stimulating Gq-mediated cellular signaling and in allosterically promoting Gq coupling. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Specifiche

Specifiche e purezza

≥99%

Meccanismi biochimici e fisiologici

TRV056 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV056 is efficacious in stimulating cellular Gq-mediated signaling. TRV056 can be used to develop the Gq-biased AT1R agonists.

Condizioni di conservazione di stoccaggio

Protected from light,Argon charged,Desiccated,Store at -80°C

Spedito in

Dry ice packs + Cold packs

Questo prodotto richiede spedizione a catena fredda. I servizi di terra e altri servizi economici non sono disponibili.

Purezza

≥99%

Nomi e identificatori

Peso molecolare

1103.23

Proprietà chimiche e fisiche

• Solubilità: H2O : 1.96 mg/mL (1.78 mM; ultrasonic and adjust pH to 2 with HCl)

Domande frequenti

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 812644-79-4, the molecular formula is C52H74N14O13, and the molecular weight is 1103.23 g/mol.

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?80 °C, protected from light, desiccated, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.