L134 , CAS No.L1429184
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L1429184
L134 is a potent PROTAC BRD4 degrader with a DC 50 value of 7.36 nM. L134 mediates the degradation of BRD4 via the ubiquitin-proteasome system in a DCAF11-dependent manner (Blue: JQ-1 (carboxylic acid) , Black: linker ; Pink: E3 ligase ligand, L321 ).
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| CAS | L1429184 |
|---|---|
| Condiciones de almacenamiento de almacenamiento | Store at -20°C |
| Enviado en | Ice chest + Ice pads |
| Product Description | L134 is a potent PROTAC BRD4 degrader with a DC 50 value of 7.36 nM. L134 mediates the degradation of BRD4 via the ubiquitin-proteasome system in a DCAF11-dependent manner (Blue: JQ-1 (carboxylic acid) , Black: linker ; Pink: E3 ligase ligand, L321 ). |
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