CD45 Mouse mAb - Primary antibody, specific to CD45, Mouse IgG1
En stock
SKU
Ab094898
mAb (2D1); Mouse anti Human CD45 Antibody; Flow; Unconjugated
Mouse anti Human CD45 Antibody, Monoclonal (2D1), could be used for Flow and so on.
Application
Flow: 1.0 μg/100w cells
Protein Function
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.
Plus d’information
| Cible | PTPRC |
|---|---|
| Clone | 2D1 |
| Gene Id | 5788 |
| Accession # | P08575 |
| Symbole génétique | PTPRC |
| Synonymes | B220 | CD_antigen: CD45 | CD45 antigen | CD45 | CD45R | EC 3.1.3.48 | EC:3.1.3.48 | GP180 | LCA | L-CA | Leukocyte common antigen | LY5 | protein tyrosine phosphatase, receptor type, c polypeptide | PTPRC | receptor-type tyrosine-protein phosphatase C | T |
| Spécifications et pureté | Carrier Free,ExactAb™,Azide Free,Validated,PBS Only,See COA |
| Spécificité | CD45 |
| Immunogène | Human PBMC |
| Isotype | Mouse IgG1 |
| Type de chaîne lumineuse | kappa |
| SDS-PAGE | 150 kDa |
| Méthode de purification | Protein G purified |
| Concentration | See COA |
| Product Description | Mouse anti Human CD45 Antibody, Monoclonal (2D1), could be used for Flow and so on. Application Flow: 1.0 μg/100w cells Protein Function Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. |
| Forme | Liquid |
| Conditions de stockage de stockage | Store at 2-8°C |
| Expédié en | Wet ice |
| Stabilité et stockage | Shipped at 4°C. Store at 4°C long term (12 months). Upon receipt, it is recommended to aliquot. |
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