Facteur d'initiation eucaryote (eIF)

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  1. Rocaglamide(Roc-A)
    CAS: 84573-16-0 PubChem CID: 331783 Formule: C29H31NO7 Poids moléculaire: 505.57
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Sur commande · 8–12 semaines Article #: R276055
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    Nom IUPAC
    (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
    SMILES
    CN(C)C(=O)C1C(C2(C(C1O)(C3=C(O2)C=C(C=C3OC)OC)O)C4=CC=C(C=C4)OC)C5=CC=CC=C5
    InChIKey
    DAPAQENNNINUPW-IDAMAFBJSA-N
    InChI
    1S/C29H31NO7/c1-30(2)27(32)23-24(17-9-7-6-8-10-17)29(18-11-13-19(34-3)14-12-18)28(33,26(23)31)25-21(36-5)15-20(35-4)16-22(25)37-29/h6-16,23-24,26,31,3show more
    Synonymes
    FRG4N852F7 | B603847K064 | NSC326408 | Rocaglamide | 1H-Cyclopenta(b)benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1...
  2. ATP-gamma-S
    CAS: 93839-89-5 Numéro CE: 298-862-8 Formule: C10H12Li4N5O12P3S Poids moléculaire: 546.98
    ● En stock — États-Unis Article #: A274887
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    Nom IUPAC
    tetralithium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] dioxidophosphinothioyl phosphate
    SMILES
    [Li+].[Li+].[Li+].[Li+].C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=S)([O-])[O-])O)O)N
    InChIKey
    DWQFDOIBOYDYKH-KWIZKVQNSA-J
    InChI
    1S/C10H16N5O12P3S.4Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(25-10)1-24-28(18,19)26-29(20,21)27-30(22,23)31;;;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)show more
    Synonymes
    Adenosine 5'-(γ-thio)-triphosphate (lithium salt) | P'-anhydride with phosphorothioic acid adenosine 5'-(trihydrogen ...
  3. 6-Methyl-1H-indole-2-carboxylic acid
    CAS: 18474-59-4 Formule: C10H9NO2 Poids moléculaire: 175.18
    ● En stock — États-Unis Article #: M182288
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    Nom IUPAC
    6-methyl-1H-indole-2-carboxylic acid
    SMILES
    CC1=CC2=C(C=C1)C=C(N2)C(=O)O
    InChIKey
    ZKGSVVHFMZASJS-UHFFFAOYSA-N
    InChI
    1S/C10H9NO2/c1-6-2-3-7-5-9(10(12)13)11-8(7)4-6/h2-5,11H,1H3,(H,12,13)
    Synonymes
    BDBM50305666 | 6-Methyl-1H-indole-2-carboxylic acid, AldrichCPR | MFCD02664477 | EN300-15104 | NCGC00337851-01 | ZKGS...
  4. 2-((5-(((9H-Fluoren-9-ylmethoxy)carbonyl)amino)-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-2-yl)oxy)acetic acid
    CAS: 212783-75-0 Formule: C32H27NO5 Poids moléculaire: 505.56
    Solid ≥98%
    ◐ .Sur commande · 8–12 semaines Article #: S117934
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    Nom IUPAC
    2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-tricyclo[9.4.0.03,8]pentadeca-1(15),3(8),4,6,11,13-hexaenyl]oxy]acetic acid
    SMILES
    C1CC2=C(C=CC(=C2)OCC(=O)O)C(C3=CC=CC=C31)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
    InChIKey
    XHOBPBDZGGKEOX-UHFFFAOYSA-N
    InChI
    1S/C32H27NO5/c34-30(35)19-37-22-15-16-24-21(17-22)14-13-20-7-1-2-8-23(20)31(24)33-32(36)38-18-29-27-11-5-3-9-25(27)26-10-4-6-12-28(26)29/h1-12,15-17,2show more
    Synonymes
    AC-32003 | SCHEMBL22572694 | MFCD07783960 | J-013969 | BCP16052 | FT-0643964 | 2-[[5-[[(9H-Fluoren-9-ylmethoxy)carbon...
  5. 4E1RCat
    CAS: 328998-25-0 Formule: C28H18N2O6 Poids moléculaire: 478.45
    10mM in DMSO
    ● En stock — États-Unis Article #: E423360
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    Nom IUPAC
    4-[(3Z)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
    SMILES
    C1=CC=C(C=C1)C2=CC(=CC3=CC=C(O3)C4=CC=C(C=C4)[N+](=O)[O-])C(=O)N2C5=CC=C(C=C5)C(=O)O
    InChIKey
    BBQRBOIMSKMFFO-PGMHBOJBSA-N
    InChI
    1S/C28H18N2O6/c31-27-21(16-24-14-15-26(36-24)19-6-12-23(13-7-19)30(34)35)17-25(18-4-2-1-3-5-18)29(27)22-10-8-20(9-11-22)28(32)33/h1-17H,(H,32,33)/b21-show more
    Synonymes
    4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
  6. 4E1RCat
    CAS: 328998-25-0 Formule: C28H18N2O6 Poids moléculaire: 478.45
    ● En stock — États-Unis Article #: E345401
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    Nom IUPAC
    4-[(3Z)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
    SMILES
    C1=CC=C(C=C1)C2=CC(=CC3=CC=C(O3)C4=CC=C(C=C4)[N+](=O)[O-])C(=O)N2C5=CC=C(C=C5)C(=O)O
    InChIKey
    BBQRBOIMSKMFFO-PGMHBOJBSA-N
    InChI
    1S/C28H18N2O6/c31-27-21(16-24-14-15-26(36-24)19-6-12-23(13-7-19)30(34)35)17-25(18-4-2-1-3-5-18)29(27)22-10-8-20(9-11-22)28(32)33/h1-17H,(H,32,33)/b21-show more
    Synonymes
    4-[(3E)-3-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenylpyrrol-1-yl]benzoic acid
  7. 4E2RCat
    CAS: 432499-63-3 PubChem CID: 2287236 Formule: C22H14ClNO4S2 Poids moléculaire: 455.93
    ≥98% mixture of isomers
    ● En stock — États-Unis Article #: E412440
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    Nom IUPAC
    5-[5-[(Z)-(3-benzyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]furan-2-yl]-2-chlorobenzoic acid
    SMILES
    C1=CC=C(C=C1)CN2C(=O)C(=CC3=CC=C(O3)C4=CC(=C(C=C4)Cl)C(=O)O)SC2=S
    InChIKey
    WOBPZFKXPCYOLU-ODLFYWEKSA-N
    InChI
    1S/C22H14ClNO4S2/c23-17-8-6-14(10-16(17)21(26)27)18-9-7-15(28-18)11-19-20(25)24(22(29)30-19)12-13-4-2-1-3-5-13/h1-11H,12H2,(H,26,27)/b19-11-
    Synonymes
    PD103111 | BS-51906 | 5-[5-[(Z)-(3-benzyl-4-oxo-2-thioxo-thiazolidin-5-ylidene)methyl]-2-furyl]-2-chloro-benzoic acid...
  8. Briciclib, G1/S-specific cyclin D1 inhibitor
    CAS: 865783-99-9 PubChem CID: 11248490 Formule: C19H23O10PS Poids moléculaire: 474.42
    ● En stock — États-Unis Article #: B413506
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    Nom IUPAC
    [2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]phenyl] dihydrogen phosphate
    SMILES
    COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)OP(=O)(O)O
    InChIKey
    LXENKEWVEVKKGV-BQYQJAHWSA-N
    InChI
    1S/C19H23O10PS/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22/h5-11H,12H2,1-4H3,(H2,20,21,22)/b8-7+
    Synonymes
    AC-36098 | s6533 | 2-Methoxy-5-(((2-(2,4,6-trimethoxyphenyl)ethenyl)sulfonyl)methyl)phenyl dihydrogen phosphate | Bri...
  9. Briciclib, G1/S-specific cyclin D1 inhibitor
    CAS: 865783-99-9 PubChem CID: 11248490 Formule: C19H23O10PS Poids moléculaire: 474.42
    10mM in DMSO
    ● En stock — États-Unis Article #: B426444
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    Nom IUPAC
    [2-methoxy-5-[[(E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonylmethyl]phenyl] dihydrogen phosphate
    SMILES
    COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)OP(=O)(O)O
    InChIKey
    LXENKEWVEVKKGV-BQYQJAHWSA-N
    InChI
    1S/C19H23O10PS/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22/h5-11H,12H2,1-4H3,(H2,20,21,22)/b8-7+
    Synonymes
    AC-36098 | s6533 | 2-Methoxy-5-(((2-(2,4,6-trimethoxyphenyl)ethenyl)sulfonyl)methyl)phenyl dihydrogen phosphate | Bri...
  10. Episilvestrol
    CAS: 697235-39-5 Formule: C34H38O13 Poids moléculaire: 654.66
    ◐ .Sur commande · 8–12 semaines Article #: E126128
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    Nom IUPAC
    methyl (1R,2R,3S,3aR,8bS)-6-[[(2S,3R,6R)-6-[(1S)-1,2-dihydroxyethyl]-3-methoxy-1,4-dioxan-2-yl]oxy]-1,8b-dihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phshow more
    SMILES
    COC1C(OC(CO1)C(CO)O)OC2=CC3=C(C(=C2)OC)C4(C(C(C(C4(O3)C5=CC=C(C=C5)OC)C6=CC=CC=C6)C(=O)OC)O)O
    InChIKey
    GVKXFVCXBFGBCD-JRPGFILLSA-N
    InChI
    1S/C34H38O13/c1-40-20-12-10-19(11-13-20)34-27(18-8-6-5-7-9-18)26(30(38)42-3)29(37)33(34,39)28-23(41-2)14-21(15-24(28)47-34)45-32-31(43-4)44-17-25(46-3show more
    Synonymes
    DTXSID80466766 | CHEBI:66485 | Episilvestrol | epi-silvestrol | EX-A4881 | MS-30981 | HY-15359 | methyl (1R,2R,3S,3aR...
  11. GCN2iB
    CAS: 2183470-12-2 Formule: C18H12ClF2N5O3S Poids moléculaire: 451.83
    ● En stock — États-Unis Article #: G414275
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    Nom IUPAC
    N-[3-[2-(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl]-5-chloro-2-methoxypyridine-3-sulfonamide
    SMILES
    COC1=C(C=C(C=N1)Cl)S(=O)(=O)NC2=C(C(=C(C=C2)F)C#CC3=CN=C(N=C3)N)F
    InChIKey
    JGHVXJKGYJYWOP-UHFFFAOYSA-N
    InChI
    1S/C18H12ClF2N5O3S/c1-29-17-15(6-11(19)9-23-17)30(27,28)26-14-5-4-13(20)12(16(14)21)3-2-10-7-24-18(22)25-8-10/h4-9,26H,1H3,(H2,22,24,25)
    Synonymes
    N-[3-[2-(2-Amino-5-pyrimidinyl)ethynyl]-2,4-difluorophenyl]-5-chloro-2-methoxy- 3-pyridinesulfonamide
  12. GCN2iB
    CAS: 2183470-12-2 Formule: C18H12ClF2N5O3S Poids moléculaire: 451.83
    10mM in DMSO
    ● En stock — États-Unis Article #: G422624
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    Nom IUPAC
    N-[3-[2-(2-aminopyrimidin-5-yl)ethynyl]-2,4-difluorophenyl]-5-chloro-2-methoxypyridine-3-sulfonamide
    SMILES
    COC1=C(C=C(C=N1)Cl)S(=O)(=O)NC2=C(C(=C(C=C2)F)C#CC3=CN=C(N=C3)N)F
    InChIKey
    JGHVXJKGYJYWOP-UHFFFAOYSA-N
    InChI
    1S/C18H12ClF2N5O3S/c1-29-17-15(6-11(19)9-23-17)30(27,28)26-14-5-4-13(20)12(16(14)21)3-2-10-7-24-18(22)25-8-10/h4-9,26H,1H3,(H2,22,24,25)
    Synonymes
    3-​Pyridinesulfonamide,N-​[3-​[2-​(2-​amino-​5-​pyrimidinyl)​ethynyl]​-​2,​4-​difluorophenyl]​-​5-​chloro-​2-​methoxy-
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Foire aux questions

What can I find under Eukaryotic Initiation Factor (eIF)?
This listing collects compounds associated with Eukaryotic Initiation Factor (eIF) within our Cell Cycle/DNA Damage area — inhibitors, agonists or antagonists, and reference tool compounds. Each entry links to its structure, CAS number, and reported activity so you can confirm the annotation before ordering.
What should I consider when picking a compound for Eukaryotic Initiation Factor (eIF)?
Consider the reported potency of each Eukaryotic Initiation Factor (eIF) compound and the assay behind it, selectivity against closely related targets, cell permeability if you are working in cells, and stability in your buffer. Two chemically distinct compounds giving the same phenotype is much stronger evidence than one.
What quality information is provided for Eukaryotic Initiation Factor (eIF) compounds?
Each Eukaryotic Initiation Factor (eIF) product page lists purity, identity data, molecular formula and weight, and storage conditions, with a lot-specific Certificate of Analysis available. Solubility and handling notes are on the datasheet. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Eukaryotic Initiation Factor (eIF) compounds by activity or structure?
Yes. Filter the Eukaryotic Initiation Factor (eIF) listing by mechanism — inhibitor, agonist, antagonist — and search by target name or gene symbol, CAS number, molecular formula, or SMILES to reach exact structures and close analogs. For bulk quantities or items not listed, contact [email protected].

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